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This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Article

Laser Acupuncture versus Liraglutide in Treatment of Obesity: A Multi-Institutional Retrospective Cohort Study

by
Wen-Lin Yu
1,†,
Yu-Ning Liao
1,†,
Tsung-Hsien Yang
1,
Ching-Wei Yang
1,2,
Ting-I Kao
1,
Pai-Wei Lee
3,
Chiu-Yi Hsu
3,
Jhen-Ling Huang
3,
Yu-Tung Huang
3 and
Hsing-Yu Chen
1,2,4,*
1
Division of Chinese Internal Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan
2
School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
3
Center for Big Data Analytics and Statistics, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan 333, Taiwan
4
Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Healthcare 2024, 12(13), 1279; https://0-doi-org.brum.beds.ac.uk/10.3390/healthcare12131279
Submission received: 6 April 2024 / Revised: 15 June 2024 / Accepted: 16 June 2024 / Published: 26 June 2024
(This article belongs to the Special Issue Emerging Developments in Integrative and Complementary Medicine: Advancements in Research and Clinical Applications)
Review Reports Versions Notes

Abstract

Background: Obesity is a global concern, driving the search for alternative treatments beyond lifestyle changes and medications. Laser acupuncture (LA) shows promise in obesity management, yet few studies compare it with FDA-approved medications. This study aimed to assess and compare LA’s impact with liraglutide on weight reduction in obese individuals. Methods: Data from the Chang Gung Research Database (CGRD) (2013–2018) were analyzed. Primary outcomes included changes in body weight and BMI within 180 days, with secondary outcomes measuring the proportion achieving 5%, 10%, and 15% weight loss. Adverse events were also assessed. Results: Of 745 subjects (173 LA users, 572 liraglutide users), LA users lost more weight by day 180 (5.82 ± 4.39 vs. 2.38 ± 5.75 kg; p < 0.001) and had a greater BMI reduction (−2.27 ± 1.73 vs. −0.93 ± 2.25 kg/m2; p < 0.001). More LA users achieved 5% and 10% weight loss compared to liraglutide users (64.2% vs. 22.7%, 26.6% vs. 4.2%; all p < 0.001). After balancing baseline differences, LA’s benefits remained significant. No adverse events were reported with LA. Conclusions: LA may offer superior weight reduction compared to liraglutide. Future studies should explore LA alone or in combination with liraglutide for obesity management.
Keywords: laser acupuncture; integrative and complementary medicine; obesity; body weight loss laser acupuncture; integrative and complementary medicine; obesity; body weight loss

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MDPI and ACS Style

Yu, W.-L.; Liao, Y.-N.; Yang, T.-H.; Yang, C.-W.; Kao, T.-I.; Lee, P.-W.; Hsu, C.-Y.; Huang, J.-L.; Huang, Y.-T.; Chen, H.-Y. Laser Acupuncture versus Liraglutide in Treatment of Obesity: A Multi-Institutional Retrospective Cohort Study. Healthcare 2024, 12, 1279. https://0-doi-org.brum.beds.ac.uk/10.3390/healthcare12131279

AMA Style

Yu W-L, Liao Y-N, Yang T-H, Yang C-W, Kao T-I, Lee P-W, Hsu C-Y, Huang J-L, Huang Y-T, Chen H-Y. Laser Acupuncture versus Liraglutide in Treatment of Obesity: A Multi-Institutional Retrospective Cohort Study. Healthcare. 2024; 12(13):1279. https://0-doi-org.brum.beds.ac.uk/10.3390/healthcare12131279

Chicago/Turabian Style

Yu, Wen-Lin, Yu-Ning Liao, Tsung-Hsien Yang, Ching-Wei Yang, Ting-I Kao, Pai-Wei Lee, Chiu-Yi Hsu, Jhen-Ling Huang, Yu-Tung Huang, and Hsing-Yu Chen. 2024. "Laser Acupuncture versus Liraglutide in Treatment of Obesity: A Multi-Institutional Retrospective Cohort Study" Healthcare 12, no. 13: 1279. https://0-doi-org.brum.beds.ac.uk/10.3390/healthcare12131279

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