The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology: A Retrospective Review
Abstract
:1. Introduction
2. Papanicolaou Society of Cytopathology Categories and Nomenclature
2.1. Category I
2.2. Category II
2.3. Category III
2.4. Category IV
2.5. Category V
2.6. Category VI
3. Summary
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
- Pitman, M.B.; Centeno, B.A.; Ali, S.Z.; Genevay, M.; Stelow, E.; Mino-Kenudson, M. Standardized terminology and nomenclature for pancreaticobiliary cytology The Papanicolaou Society of Cytopathology Guidelines. Diagn. Cytopathol. 2014, 42, 338–350. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Pitman, M.B.; Layfield, L.J. The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology; Springer: Berlin/Heidelberg, Germany, 2015. [Google Scholar] [CrossRef]
- Sung, S.; Del Portillo, A.; Gonds, T.A.; Kluger, M.; Tiscornia-Wasserman, P.G. Update on risk stratification in the Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology categories: 3-year, prospective, single-institution experience. Cancer Cytopathol. 2020, 128, 29–35. [Google Scholar] [CrossRef] [PubMed]
- Wright, P.K.; Shelton, D.A.; Holbrook, M.R.; Thiryayi, S.A.; Narine, N.; Slater, D.; Rana, D.N. Outcomes of endoscopic ultrasound-guided pancreatic FNAC diagnosis for solid and cystic lesions at Manchester Royal Infirmary based upon the Papanicolaou Society of Cytopathology pancreaticobiliary terminology classification scheme. Cytopathology 2018, 29, 71–79. [Google Scholar] [CrossRef] [PubMed]
- Layfield, L.J.; Dodd, L.; Factor, R.; Schmidt, R.L. Malignancy risk associated with diagnostic categories defined by the Papanicolaou Society of Cytopathology pancreaticobiliary guidelines. Cancer Cytopathol. 2014, 122, 420–427. [Google Scholar] [CrossRef] [PubMed]
- Hoda, R.S.; Finer, E.B.; Arpin, R.N., III; Rosenbaum, M.; Pitman, M.B. Risk of malignancy in the categories of the Papanicolaou Society of Cytopathology system for reporting pancreaticobiliary cytology. Jam Soc. Cytopathol. 2019, 8, 120–127. [Google Scholar] [CrossRef] [PubMed]
- Brugge, W.R.; Lewandrowski, K.; Lee-Lewandrowski, E.; Centeno, B.A.; Szydlo, T.; Regan, S. Diagnosis of pancreatic cystic neoplasms: A report of the cooperative pancreatic cyst study. Gastroenterology 2004, 40, 1024–1028. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Cizginer, S.; Turner, B.; Bilge, A.B.; Karaca, C.; Pitman, M.B.; Brugge, W.R. Cyst fluid carcinoembryonic antigen is an accurate diagnostic marker of pancreatic mucinous cysts. Pancreas 2011, 40, 1024–1028. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Nikiforova, M.N.; Khalid, A.; Fasanella, K.; McGrath, K.M.; Brand, R.; Chennat, J.S.; Slivka, A.; Zeh, H.J.; Zureikat, A.H.; Krasinskas, A.M.; et al. Integration of KRAS testing in the diagnosis of pancreatic cystic lesions: A clinical experience of 618 pancreatic cysts. Mod. Pathol. 2013, 26, 1478–1487. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Wu, J.; Matthaei, H.; Maitra, A.; Dal Molin, M.; Wood, L.D.; Eshleman, J.R. Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development. Sci. Transl. Med. 2011, 3, 92ra66. [Google Scholar] [CrossRef] [PubMed] [Green Version]
Category | Malignancy Risk | ||
---|---|---|---|
All Categories + | FNA | Sputum | |
Non-Diagnostic | 50 to 64% | 0 to 40% | Up to 100% |
Negative (Benign) | 40 to 45% | 6 to 25% | 40% |
Atypical | 50 to 60% | 45 to 54% | 50% |
Neoplasm | unknown * | unknown * | unknown * |
Suspicious for Malignancy | 90% | 75 to 84% | 90% |
Malignant | 90% | 86 to 100% | 90% |
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Layfield, L.J. The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology: A Retrospective Review. J. Mol. Pathol. 2021, 2, 101-108. https://0-doi-org.brum.beds.ac.uk/10.3390/jmp2020010
Layfield LJ. The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology: A Retrospective Review. Journal of Molecular Pathology. 2021; 2(2):101-108. https://0-doi-org.brum.beds.ac.uk/10.3390/jmp2020010
Chicago/Turabian StyleLayfield, Lester J. 2021. "The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology: A Retrospective Review" Journal of Molecular Pathology 2, no. 2: 101-108. https://0-doi-org.brum.beds.ac.uk/10.3390/jmp2020010