Protease Dynamics on the Membrane: From Structure to Function
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Biochemistry and Molecular Biology".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 430
Special Issue Editors
2. Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, USA
Interests: structure–function relationship; computational enzymology and receptology; protein–protein and protein–lipid interactions
Interests: molecular mechanisms for (de)activation and disorder in coagulation cascade and signaling pathways; computational methodologies for structural molecular biology
Special Issue Information
Dear Colleagues,
In this Special Issue entitled “Protease Dynamics on the Membrane: From Structure to Function”, we hope to advance the research areas that focus on the structure–function relation of proteases and its binding molecules that are important in health maintenance and disease treatments, especially when cellular membranes play important roles. The target molecules therefore include but are not limited to enzymes, substrates, cofactors, inhibitors, adaptors, receptors, their mutants, drugs, and membrane lipids.
We call for such studies employing experimental or computational approaches, or both. Investigations on the mechanisms of how structural changes upon complex formation and/or membrane binding alter the function of molecule of interest are particularly welcome. By collecting clear, concise, and high-quality original research articles and reviews, we hope this Special Issue will help to drive the field forward.
Dr. Jesper J. Madsen
Dr. Y. Zenmei Ohkubo
Guest Editors
Manuscript Submission Information
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Keywords
- protein–protein interactions
- protein–lipid interactions
- complex formation
- protease
- membrane binding
- coagulation
- complement
- cancer
