Advances in Tumor Vascular Imaging

Dear Colleagues,

Intralesional (tumoral) blood vessels of neoplasms, as well as feeding arteries and draining veins, are essential for nutrient supply, the discharge of waste products, and the invasion and remote metastasis of tumor cells. There are strong correlations between tumor viability and their vascularity in various tumors. Measurement of tumor vascularity is useful not only in tumor diagnosis and treatment efficacy determination, but also in surgical planning to prevent serious bleeding. For example, external irradiations such as stereotactic radiosurgery, some embolic substances and several molecular-targeting drugs, including bevacizumab (anti-VEGF antibody), can decrease tumor vascularity; therefore, their measurement is useful in determining efficacy. Various challenges have been posed by imaging-using techniques such as magnetic resonance imaging (MRI), computed tomography (CT), angiography and single-photon ECT (SPECT) in the quantification of tumor vascularity and identification of vascular features including arterial feeding vessels and tumor neovascularization. More recently, PET imaging and other imaging modalities have also been used to detect tumor vascularity.

In this Special Issue, we welcome original papers and review articles that provide an overview of the latest advances and future challenges in tumor vascular imaging for the diagnosis and treatment of various neoplasms and neoplasmic mimics.

Dr. Eiichi Ishikawa
Guest Editor

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