Arrhythmic Mitral Valve Prolapse: Risk Factors, Pathophysiology and Risk Stratification for Cardiac Arrhythmias

Dear Colleagues,

Mitral valve prolapse is a common valvular disorder affecting about 2–3% of the general population. While the majority of cases have benign outcomes, there is a specific subset of patients for whom mitral valve prolapse is associated with malignant ventricular arrhythmias and sudden cardiac death. This specific patient subset is classed as having arrhythmic mitral valve prolapse. Sudden cardiac arrest can occur in young patients with mitral valve prolapse, which can be a devastating event. The link between sudden cardiac death and mitral valve prolapse is increasingly being recognised. However, the underlying pathophysiology and risk factors are incompletely understood and risk stratification methods remain poorly defined.

This Special Issue will focus on defining the risk factors, exploring the pathophysiology in arrhythmic mitral valve prolapse, and describing the current challenges in risk stratification for sudden cardiac death in this cohort of patients.

Dr. Han Lim
Guest Editor

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• mitral valve prolapse
• mitral annular disjunction
• arrhythmia
• sudden cardiac death
• risk stratification