Food, Drugs and Environmental Exposures as Triggers of Myocardial Injury and Myocardial Infarction

Dear Colleagues,

Hippocrates, the father of Medicine, once said “Let food be your medicine and medicine be your food.” Indeed, there are important and significant associations between the frequency of one’s consumption of specific foods and the subsequent risk of myocardial infarction. The role of food in health has been evidenced via epidemiological observations and associated studies, in which a single or limited number of foods have demonstrated the diet–disease relationships. Environmental factors, and diet in particular, are known to play a key role in the development of coronary artery disease. Many of these factors have been unveiled by nutritional observations, focusing on the role of a single nutrient or food.

Moreover, therapeutic and illicit drug use are documented and lead to the consideration of alternative pathophysiologic rationales for myocardial infarction. The drugs employed for the treatment of cancer, central nervous system stimulants, allergy-induced medications and a plethora of other drugs with cytotoxic and hypersensitivity actions possess the potential to induce myocardial damage.

Growing evidence suggests that there is an association between exposure to ambient air pollution, household air pollution from biomass fuel, lead, arsenic, and cadmium and multiple cardiovascular disease outcomes, including myocardial damage, hypertension, coronary heart disease, stroke, and cardiovascular mortality. The aim of this Special Issue is to describe the association between foods, drugs and the environment, and coronary damage and disease. This will improve the knowledge, prevention and treatment of these frequent daily exposures.

Prof. Dr. Nicholas G Kounis
Guest Editor

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• myocardial injury
• myocardial infarction
• diet
• drugs
• environmental exposures