Identification and Characterization of Marine Natural Compounds Targeting Nuclear, Ionotropic, or Metabotropic Receptors
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (20 March 2022) | Viewed by 5680
Special Issue Editors
Interests: nuclear receptor; lipid metabolism; epigenetics; DNA methylation; antifouling; transcriptional regulation
Interests: molecular docking; molecular dynamics; virtual screening; natural products; drug design; structure-activity relationships
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Marine natural products are an invaluable source of new leads in drug discovery due to their highly diverse molecular scaffolds and functional groups. So far, many natural bioactive compounds have been identified as modulators of nuclear receptors, including PPARs, RARs and RXRs, transmembrane receptors, such as GPCRs and those belonging to the TRP receptor-channel family. All these receptor classes represent relevant pharmacological targets for the treatment of a wide range of physio-pathological processes, including pain, inflammation, cancer, metabolic and neurological diseases. In this context, for this Special Issue, we aim to collect original research and review articles focused on the discovery of marine compounds active on these targets that are potentially useful for the treatment of the related pathologies. In vivo studies using vertebrate and/or invertebrate model organisms would be particularly appreciated.
Dr. Enrico D'Aniello
Dr. Rosa Maria Vitale
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- marine compounds
- drug discovery
- nuclear receptor
- transmembrane receptor
- physio-pathology
- in vivo
