Microbial Manufacture of Natural Products

Dear Colleagues,

The field of microbial manufacture of natural products focuses on harnessing the power of microorganisms to produce a wide range of valuable compounds. Microbial cell factories are extensively employed for the sustainable production of high-value chemicals. With rapid societal progress, humanity faces common pressures related to energy, environment, population, and resources. In recent years, the microbial manufacturing industry has garnered significant attention due to its utilization of renewable raw materials and implementation of clean and efficient processes. There is an enormous demand in various sectors including pharmaceuticals, food, chemical, and energy industries. However, the intricate nature of microbial cell metabolism often results in limited production capacities when synthesizing natural products. The Special Issue "Microbial Manufacture of Natural Products" in Microorganisms presents research on bioproduction pathways and methods utilized by industrial bacteria, actinomycetes, and fungi for producing high-value natural products. It encourages the description of novel biotechnological solutions for metabolite biosynthesis along with their applications in the fields of food/feed processing as well as chemical and medical industries. Studies investigating antimicrobial or bioactive properties of natural products will be given particular consideration within this collection.

1. Systems biology and synthetic biology in the context of cellular manufacturing:

(a) Innovative bacterial biosynthesis of metabolites or antimicrobial bioactive compounds;

(b) Extraction, refinement, and elucidation of the chemical properties of metabolites produced by cellular manufacturing systems.

2. Microbial production processes:

(a) Optimizing the biosynthetic pathways and fermentation process for secondary metabolites, peptides, amino acids, and organic acids;

(b) Exploring alternative biosynthetic strategies as alternatives to chemical synthesis.

Dr. Liang Wang
Prof. Dr. Xusheng Chen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• metabolic regulation
• systems biology
• synthetic biology
• optimization of fermentation processes
• downstream technology