Trematode Infections: The Asian Perspective

Dear Colleagues,

The Trematoda class contains a large number of species that can infect humans, and many of the diseases they cause are listed as neglected tropical diseases (NTDs) by the World Health Organization (WHO). More than 75 million people currently live in areas endemic for food-borne, trematode (FBT) infections, which affect either the lungs, liver or intestines. This, together with the fact that that 40–50 million humans are actually infected by this kind of flukes, is testament to the fact that FBTs have changed from parasitic affections of poor people living in limited geographical areas to become serious, emerging diseases. This Special Issue focuses on human trematode infections in Asia, on the one hand including FBT infections caused by the genera Clonorchis, Opisthorchis, Paragonimus, and Fasciola and on the other, schistosomiasis cased by Schistosoma japonicum and S. mekongi. The two latter are altogether different from the FBTs as they neither are food-borne nor affect only specific, single organs. Conjoint with economic development and changing demography in Southeast Asia during the last 30 years, the geographical distribution of FBTs has expanded and the populations at risk have grown, while for schistosomiasis, the end is in sight thanks to a worldwide call for its elimination. What all these trematode flukes have in common are complicated life cycles involving various snail species as intermediate hosts, an association with poverty, a limited number of drugs available for treatment, and lack of sufficiently sensitive diagnostic methods. We intend for this Special Issue of Tropical Medicine and Infectious Disease to cover recent progress in developing new therapeutics and diagnostic tools, as well as other interventions and surveillance approaches leading to the control and elimination of these insidious parasites.

Prof. Dr. Robert Bergquist
Prof. Dr. Darren Gray
Prof. Dr. Donald McManus
Guest Editors

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• Clonorchis
• Opisthorchis
• Paragonimus
• Fasciola
• japonicum
• mekongi
• Asia
• Epidemiology
• Control
• Matematical modelling
• Diagnostics
• Chemotherapy
• Snail control
• Transmission
• Zoonoses
• One Health