Zebrafish Neural Development in Toxicological Studies

Dear Colleagues,

The development of the central nervous system is a complex process dependent on genetic and molecular mechanisms that coordinate cells from proliferation to tissue organization. The key features of these mechanisms are phylogenetically conserved. Over the years, animal models have been widely used to study the neurotoxicological impact of different compounds. In addition to rodents, the zebrafish has gained popularity as a translational animal model. In particular, the zebrafish embryo transparency, fast brain development, and its organizational homology with higher vertebrates are important advantages to in vivo studies. Recent research has highlighted the need for a comprehensive neurotoxicity assessment for different compounds, to avoid risks to the environment or animal/human health/welfare. This can be based on the reactive oxygen species, gene expression patterns, cell death, neural morphogenesis and behavioural endpoints.

Therefore, we are pleased to invite all experts in the field of developmental neurotoxicity who work with zebrafish to contribute to this Special Issue of Veterinary Sciences with original research or review articles.

The contributions should be focused on the use of zebrafish, as a neural development model, for screening the safety of environmental compounds or others used in animals and humans, contributing with important information for the One Health and One Welfare approach.

Dr. Carlos Alberto e Silva Venâncio
Dr. Luís Félix
Dr. Sandra Mariza Monteiro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Veterinary Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• animal model
• behavioural
• brain development
• cell death
• compounds screening
• morphogenesis
• neurotoxicity
• one health
• oxidative stress
• zebrafish