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Review
Peer-Review Record

Cutaneous Metastasis after Surgery, Injury, Lymphadenopathy, and Peritonitis: Possible Mechanisms

Int. J. Mol. Sci. 2019, 20(13), 3286; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms20133286
by Isao Otsuka
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Reviewer 3: Anonymous
Int. J. Mol. Sci. 2019, 20(13), 3286; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms20133286
Submission received: 17 May 2019 / Revised: 27 June 2019 / Accepted: 1 July 2019 / Published: 4 July 2019
(This article belongs to the Special Issue Tumor Cell Invasion and Metastases)

Round 1

Reviewer 1 Report

This is a well written and interesting manuscript – review regarding “Cutaneous Metastasis after Surgery, Injury, Lymphadenopathy, and Peritonitis: Possible Mechanisms”. However, there are some comments that could be considered as follow:

 

1. Another table summarizing the pathophysiological mechanisms of cutaneous metastases would be useful.


Author Response

Thank you for your comment. 

I added a new figure depicting “possible mechanisms of skin metastases.”

Reviewer 2 Report

good paper

Author Response

Thank you very much.

Reviewer 3 Report

Page 1, Line 16 - please use another word than hijacked

Table 1 - for SJN examples, there exists a case of SJN secondary to appendiceal carcinoma as well, which should be included in the manuscript. See PMID: 29719746

Line 115 - please fix the phrase "can be occur"

Line 182 - fix "that an organisms use" to singular or plural 

Author Response

In the abstract, I replace “hijack” with “exploit.” 


The paper in “Cureus 2018” are included in the reference.


Thank you for indicating grammatical errors. I have fixed this error.


This sentence was removed, because I rewrote this part. 

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