VDAC—A Primal Perspective
Abstract
:1. Introduction
2. Folding the Chemiosmotic Membrane
3. Communication at the Host–Endosymbiont Interface
3.1. Metabolite Transport
3.2. Protein Import
4. VDAC Regulates Outer Membrane Integrity
5. VDAC Structure and Gating
5.1. Gating Is Intrinsic to VDAC
5.2. VDAC Occurs as an Ensemble of Conformers
5.3. VDAC Gating Is a Stress Sensor
6. Possible Origin of VDAC’s Flexibility
7. Conclusions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Mannella, C.A. VDAC—A Primal Perspective. Int. J. Mol. Sci. 2021, 22, 1685. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22041685
Mannella CA. VDAC—A Primal Perspective. International Journal of Molecular Sciences. 2021; 22(4):1685. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22041685
Chicago/Turabian StyleMannella, Carmen A. 2021. "VDAC—A Primal Perspective" International Journal of Molecular Sciences 22, no. 4: 1685. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22041685