Association of Economic Status and Mortality in Patients with Acute Respiratory Distress Syndrome
Abstract
:1. Introduction
2. Materials and Methods
2.1. Ethical Statement
2.2. Data Source
2.3. Study Population
2.4. Income Level as An Independent Variable
2.5. Study Endpoint
2.6. Confounders
2.7. Statistical Analysis
3. Results
3.1. Patients
3.2. Survival Analysis According to Income Level
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Variable | Total (14,600), n (%) | Mean (SD) | |
---|---|---|---|
Age, year | 69.8 (15.3) | ||
Gender, male | 9065 (62.1) | ||
Residence at diagnosis | |||
Capital city, Seoul | 2402 (16.5) | ||
Other metropolitan city a | 3334 (22.8) | ||
Others | 8864 (60.7) | ||
Income level at diagnosis | |||
Q1 | 2449 (16.8) | ||
Q2 | 2732 (18.7) | ||
Q3 | 4199 (28.8) | ||
Q4 | 5220 (35.8) | ||
Length of hospital stay, day | 16.2 (15.0) | ||
Duration of treatment, day | 18.4 (17.1) | ||
ECMO use for treatment | 681 (4.7) | ||
Comorbidities before diagnosis | |||
Hypertension | 9735 (66.7) | ||
Coronary artery disease | 4403 (30.2) | ||
Diabetes mellitus | 6500 (44.5) | ||
Cerebrovascular disease | 5044 (34.5) | ||
Lung cancer | 1125 (7.7) | ||
Chronic kidney disease | 1434 (9.8) | ||
Dyslipidemia | 8021 (54.9) | ||
Anemia | 2733 (18.7) | ||
COPD | 3819 (26.2) | ||
Asthma | 1809 (12.4) | ||
Arrhythmia | 1017 (7.0) | ||
Liver cirrhosis | 408 (2.8) | ||
Diagnosis per year | |||
2013 | 1978 (13.5) | ||
2014 | 2089 (14.3) | ||
2015 | 2065 (14.1) | ||
2016 | 2289 (15.7) | ||
2017 | 6179 (42.3) |
Variable | 30-Day Mortality | p | 1-Year Mortality | p | |
---|---|---|---|---|---|
HR (95% CI) | HR (95% CI) | ||||
Income level at ARDS diagnosis | |||||
Q1 | 1 | 1 | |||
Q2 | 1.02 (0.94, 1.10) | 0.719 | 0.99 (0.93, 1.06) | 0.762 | |
Q3 | 1.00 (0.93, 1.08) | 0.946 | 0.98 (0.92, 1.04) | 0.420 | |
Q4 | 0.98 (0.91, 1.05) | 0.542 | 0.96 (0.91, 1.02) | 0.189 | |
Age, year | 1.02 (1.01, 1.02) | <0.001 | 1.02 (1.01, 1.02) | <0.001 | |
Gender, male | 1.00 (0.95, 1.05) | 0.895 | 1.03 (0.99, 1.07) | 0.167 | |
Residence at diagnosis | |||||
Capital city, Seoul | 1 | 1 | |||
Other metropolitan city | 1.18 (1.09, 1.27) | <0.001 | 1.12 (1.06, 1.20) | <0.001 | |
Others | 1.11 (1.04, 1.19) | 0.002 | 1.04 (0.98, 1.09) | 0.211 | |
ECMO use for treatment | 1.30 (1.16, 1.45) | <0.001 | 1.38 (1.25, 1.52) | <0.001 | |
Comorbidity before diagnosis | |||||
Hypertension | 0.92 (0.87, 0.97) | 0.004 | 0.93 (0.89, 0.97) | 0.002 | |
Coronary artery disease | 0.97 (0.92, 1.03) | 0.285 | 0.95 (0.91, 1.00) | 0.029 | |
Diabetes mellitus | 0.99 (0.94, 1.04) | 0.687 | 0.98 (0.94, 1.02) | 0.397 | |
Cerebrovascular disease | 0.89 (0.84, 0.94) | <0.001 | 0.93 (0.89, 0.97) | 0.002 | |
Lung cancer | 0.99 (0.91, 1.08) | 0.799 | 1.09 (1.02, 1.17) | 0.017 | |
Chronic kidney disease | 0.80 (0.73, 0.87) | <0.001 | 0.84 (0.78, 0.90) | <0.001 | |
Dyslipidemia | 1.06 (1.00, 1.12) | 0.039 | 1.07 (1.02, 1.12) | 0.004 | |
Anemia | 0.94 (0.88, 1.00) | 0.050 | 0.95 (0.87, 1.03) | 0.182 | |
COPD | 0.76 (0.71, 0.80) | <0.001 | 0.77 (0.74, 0.81) | <0.001 | |
Asthma | 0.98 (0.90, 1.06) | 0.539 | 0.96 (0.90, 1.02) | 0.194 | |
Arrhythmia | 0.95 (0.86, 1.05) | 0.332 | 0.95 (0.87, 1.03) | 0.182 | |
Liver cirrhosis | 1.17 (1.01, 1.34) | 0.034 | 1.17 (1.04, 1.31) | 0.010 | |
Diagnosis per year | |||||
2013 | 1 | 1 | |||
2014 | 0.86 (0.80, 0.93) | <0.001 | 0.84 (0.78, 0.89) | <0.001 | |
2015 | 0.84 (0.78, 0.91) | <0.001 | 0.76 (0.72, 0.82) | <0.001 | |
2016 | 0.79 (0.73, 0.85) | <0.001 | 0.70 (0.66, 0.75) | <0.001 | |
2017 | 0.25 (0.23, 0.27) | <0.001 | 0.16 (0.15, 0.18) | <0.001 |
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Oh, T.K.; Song, I.-A.; Lee, J.H. Association of Economic Status and Mortality in Patients with Acute Respiratory Distress Syndrome. Int. J. Environ. Res. Public Health 2020, 17, 1815. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17061815
Oh TK, Song I-A, Lee JH. Association of Economic Status and Mortality in Patients with Acute Respiratory Distress Syndrome. International Journal of Environmental Research and Public Health. 2020; 17(6):1815. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17061815
Chicago/Turabian StyleOh, Tak Kyu, In-Ae Song, and Jae Ho Lee. 2020. "Association of Economic Status and Mortality in Patients with Acute Respiratory Distress Syndrome" International Journal of Environmental Research and Public Health 17, no. 6: 1815. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17061815