Infectious Disease Reports

428 KiB

Open AccessCase Report

An Unusual Case of Staphylococcus pasteuri Osteomyelitis

by Phillip P. Santoiemma, David M. Kalainov, Manish P. Mehta and Maureen K. Bolon

Infect. Dis. Rep. 2020, 12(2), 8523; https://0-doi-org.brum.beds.ac.uk/10.4081/idr.2020.8523 - 05 Aug 2020

Cited by 5 | Viewed by 1485

Staphylococcus pasteuri is a gram-positive organism found in food products as well as naturally occurring in air and on surfaces. We present the first known case of Staphylococcus pasteuri osteomyelitis caused by machine injection injury. The patient was treated with emergent surgical debridement [...] Read more.

Staphylococcus pasteuri is a gram-positive organism found in food products as well as naturally occurring in air and on surfaces. We present the first known case of Staphylococcus pasteuri osteomyelitis caused by machine injection injury. The patient was treated with emergent surgical debridement as well as doxycycline for a soft tissue infection. Despite targeted therapy, the infection progressed to osteomyelitis and was treated successfully with additional surgical debridement and trimethoprim-sulfamethoxazole. There is sparse information on both infections and treatment of Staphylococcus pasteuri. We present our case report as well as a review of the literature on the epidemiology, susceptibility and treatment recommendations for Staphylococcus pasteuri infections. Full article

346 KiB

Open AccessArticle

Insights into the Clinical Management of Carbapenem-Resistant Gram-Negative Infections: An Italian Retrospective Clinical Chart Review

by Guido Granata, Davide Manissero, Maria Vittoria Oppia, Keiko Tone, Bin Cai, Christopher Longshaw, Carolina Venditti and Nicola Petrosillo

Infect. Dis. Rep. 2020, 12(2), 8510; https://0-doi-org.brum.beds.ac.uk/10.4081/idr.2020.8510 - 05 Aug 2020

Viewed by 965

Abstract

There is a lack of consensus regarding management of infections with carbapenem- resistant Gram-negative (CR-GN) pathogens. This study comprised a medical chart review to assess patient management in a high CR prevalence setting. Data was collated retrospectively from medical records of patients hospitalized [...] Read more.

There is a lack of consensus regarding management of infections with carbapenem- resistant Gram-negative (CR-GN) pathogens. This study comprised a medical chart review to assess patient management in a high CR prevalence setting. Data was collated retrospectively from medical records of patients hospitalized between November 1^st, 2015 and October 31^st, 2016. Of 29 patients, 66% had respiratory tract infections. Median duration of hospitalization was 28 days and ~50% of patients were admitted to the intensive care unit, with 77% remaining for >2 weeks. Median time to obtain respiratory culture results was 5 days. Isolation of patients with diagnosed CR-GN infection took ≥5 days in >50% of patients. A majority (76%) of patients received ≥1 antibiotic before providing a specimen for culture; a total of 17 antibiotic treatments were used. Overall, 72% of patients, and 68% of those with respiratory infections, were discharged alive; 38% were discharged without further antibiotics. The difficulties in achieving effective management in patients with CR-GN infections are largely due to complex co-morbidities, a history of prior antibiotic treatment, and multiple referrals across health care facilities. Full article

531 KiB

Open AccessEditorial

SARS-CoV-2, “Common Cold” Coronaviruses’ Cross-Reactivity and “Herd Immunity”: The Razor of Ockham (1285-1347)?

by Nicola Petrosillo

Infect. Dis. Rep. 2020, 12(2), 8647; https://0-doi-org.brum.beds.ac.uk/10.4081/idr.2020.8647 - 29 May 2020

Cited by 3 | Viewed by 1042

Abstract

After the rapid spread of coronavirus-19 infectious disease (COVID-19) worldwide between February and April 2020, with a total of 5,267,419 confirmed cases and 341,155 deaths as of May 25, 2020, in the last weeks we are observing a decrease in new infections in [...] Read more.

After the rapid spread of coronavirus-19 infectious disease (COVID-19) worldwide between February and April 2020, with a total of 5,267,419 confirmed cases and 341,155 deaths as of May 25, 2020, in the last weeks we are observing a decrease in new infections in European countries, and the confirmed cases are not as severe as in the past, so much so that the number of patients transferred to intensive care for the worsening of the systemic and pulmonary disease is dramatically decreasing. [...] Full article

376 KiB

Open AccessCase Report

Acute Myocarditis as the Main Clinical Manifestation of SARS-CoV 2 Infection

by Gianluca Cuomo, Marianna Menozzi, Federica Carli, Margherita Digaetano, Alessandro Raimondi, Letizia Reggianini, Guido Ligabue, Giovanni Guaraldi and Cristina Mussini

Infect. Dis. Rep. 2020, 12(2), 8609; https://0-doi-org.brum.beds.ac.uk/10.4081/idr.2020.8609 - 13 May 2020

Cited by 4 | Viewed by 977

Abstract

We describe a case of acute myocarditis, which was reported as the main COVID-19 clinical manifestation, with a favorabile outcome. In addition to symptoms, laboratory tests (BNP and troponin), echocardiogram and cardiac MRI contributed to diagnosis. Regardless heart biopsy was not obtained, it [...] Read more.

We describe a case of acute myocarditis, which was reported as the main COVID-19 clinical manifestation, with a favorabile outcome. In addition to symptoms, laboratory tests (BNP and troponin), echocardiogram and cardiac MRI contributed to diagnosis. Regardless heart biopsy was not obtained, it is likely an immunological pathogenesis of this condition which pave the way to further therapeutic implications, since there are currently no standardized treatments. Full article

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Infect. Dis. Rep., Volume 12, Issue 2 (May 2020) – 4 articles

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