Recent Development of Gold Nanoparticles as Contrast Agents for Cancer Diagnosis
Abstract
:Simple Summary
Abstract
1. Introduction
2. Gold Nanoparticles in Cancer Diagnosis
2.1. Magnetic Resonance Imaging (MRI)
2.2. CT and Nuclear Imaging
2.3. Fluorescence Imaging
2.4. Photoacoustic Imaging
2.5. X-ray Fluorescence Imaging
2.6. Other Imaging Modelity
3. Conclusions and Perspectives
Author Contributions
Funding
Conflicts of Interest
References
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Particle Type | Size | Surface | Imaging Modality | Tumor Models | References |
---|---|---|---|---|---|
Superparamagnetic AuNCs (SPAuNCs) | 3 nm | EGFR | MRI (T2) | liver tumor (MDA-MB-468) | [62,63] |
AuNPs | 5 nm | PSMA | MRI (T1) | prostate tumor (PC3) | [64] |
AuNPs | 2, 5, 19 nm | PSMA | CT | prostate tumor (PC3) | [65] |
[198Au]AuNCs | 3 nm | GSH | SPECT | - | [66] |
64CuAuNCs | 4.5 nm | AMD3100 | PET | breast tumor (4T1) | [66,67,68] |
AuNCs | 2–6 nm | alpha-lactalbumin | fluorescence | breast tumor (MDA-MB-231) | [69] |
AuNPs | 5 nm | EGFR | PAI | A431 cells | [70] |
AuNPs | 1.9 nm | - | XRF | prostate tumor (PC3) | [71] |
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Luo, D.; Wang, X.; Burda, C.; Basilion, J.P. Recent Development of Gold Nanoparticles as Contrast Agents for Cancer Diagnosis. Cancers 2021, 13, 1825. https://0-doi-org.brum.beds.ac.uk/10.3390/cancers13081825
Luo D, Wang X, Burda C, Basilion JP. Recent Development of Gold Nanoparticles as Contrast Agents for Cancer Diagnosis. Cancers. 2021; 13(8):1825. https://0-doi-org.brum.beds.ac.uk/10.3390/cancers13081825
Chicago/Turabian StyleLuo, Dong, Xinning Wang, Clemens Burda, and James P. Basilion. 2021. "Recent Development of Gold Nanoparticles as Contrast Agents for Cancer Diagnosis" Cancers 13, no. 8: 1825. https://0-doi-org.brum.beds.ac.uk/10.3390/cancers13081825