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Hydrogel-Based Technologies for the Diagnosis of Skin Pathology

School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637457, Singapore
National Dental Centre of Singapore, 5 Second Hospital Ave, Singapore 168938, Singapore
Department of Biomedical Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China
Authors to whom correspondence should be addressed.
Received: 12 August 2020 / Revised: 1 September 2020 / Accepted: 1 September 2020 / Published: 2 September 2020
(This article belongs to the Section Technologies Reviews)
Hydrogels, swellable hydrophilic polymer networks fabricated through chemical cross-linking or physical entanglement are increasingly utilized in various biomedical applications over the past few decades. Hydrogel-based microparticles, dressings and microneedle patches have been explored to achieve safe, sustained and on-demand therapeutic purposes toward numerous skin pathologies, through incorporation of stimuli-responsive moieties and therapeutic agents. More recently, these platforms are expanded to fulfill the diagnostic and monitoring role. Herein, the development of hydrogel technology to achieve diagnosis and monitoring of pathological skin conditions are highlighted, with proteins, nucleic acids, metabolites, and reactive species employed as target biomarkers, among others. The scope of this review includes the characteristics of hydrogel materials, its fabrication procedures, examples of diagnostic studies, as well as discussion pertaining clinical translation of hydrogel systems. View Full-Text
Keywords: hydrogel; diagnosis; monitoring; skin pathology; skin diseases hydrogel; diagnosis; monitoring; skin pathology; skin diseases
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MDPI and ACS Style

Wiraja, C.; Ning, X.; Cui, M.; Xu, C. Hydrogel-Based Technologies for the Diagnosis of Skin Pathology. Technologies 2020, 8, 47.

AMA Style

Wiraja C, Ning X, Cui M, Xu C. Hydrogel-Based Technologies for the Diagnosis of Skin Pathology. Technologies. 2020; 8(3):47.

Chicago/Turabian Style

Wiraja, Christian, Xiaoyu Ning, Mingyue Cui, and Chenjie Xu. 2020. "Hydrogel-Based Technologies for the Diagnosis of Skin Pathology" Technologies 8, no. 3: 47.

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