Colonized Niche, Evolution and Function Signatures of Bifidobacterium pseudolongum within Bifidobacterial Genus
Abstract
:1. Introduction
2. Materials and Methods
2.1. Sample Collection
2.2. Analysis of Fecal Microbial Community and Composition of Bifidobacterium Species
2.3. Phylogenetic Reconstruction, Hierarchical Bayesian Clustering, Fixation Index (Fst) Caculation, Assembly Re-Annotation, and Pan-Genome Analysis
2.4. Profiles of Glucosyltransferase (GTs) and Glycoside HYDROLASES (GHs), and COG Functions
2.5. Profiles of Probiotic Effector Factors
2.6. Statistical Analysis
3. Results
3.1. Distribution of B. pseudolongum in the Gut of the Selected Mammals, and Features of B. pseudolongum-Enriched Gut Microbiota
3.2. Phylogenetic Structures and Niche Distribution
3.3. General Genomic Features
3.4. COG Functions and Profiles of Carbohydrate-Utilizing Enzymes
3.5. Probiotic Effector Molecules
3.6. Sub-Clade-Specific Evolution within B. pseudolongum
4. Discussion
5. Limitations
6. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
References
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Xiao, Y.; Zhao, J.; Zhang, H.; Zhai, Q.; Chen, W. Colonized Niche, Evolution and Function Signatures of Bifidobacterium pseudolongum within Bifidobacterial Genus. Foods 2021, 10, 2284. https://0-doi-org.brum.beds.ac.uk/10.3390/foods10102284
Xiao Y, Zhao J, Zhang H, Zhai Q, Chen W. Colonized Niche, Evolution and Function Signatures of Bifidobacterium pseudolongum within Bifidobacterial Genus. Foods. 2021; 10(10):2284. https://0-doi-org.brum.beds.ac.uk/10.3390/foods10102284
Chicago/Turabian StyleXiao, Yue, Jianxin Zhao, Hao Zhang, Qixiao Zhai, and Wei Chen. 2021. "Colonized Niche, Evolution and Function Signatures of Bifidobacterium pseudolongum within Bifidobacterial Genus" Foods 10, no. 10: 2284. https://0-doi-org.brum.beds.ac.uk/10.3390/foods10102284