Advanced Biomechanics in Bone Tissue Engineering

Dear Colleagues,

Bone tissue engineering is a complex and dynamic bone remodeling process which requires the recruitment of osteoprogenitor cells, their proliferation, differentiation, and matrix formation. Innovative bone scaffolds and implants should provide mechanical support during the repair and regeneration of damaged or diseased bones, ensuring suitable biomechanical and biochemical environments to support normal cellular activity and molecular signaling systems.

A bioinspired and biomimetic approach will explore the potentiality of evolution-engineered natural materials showing not regular and orthotropic trabecular micro-structures such as those of the cancellous bone, marine sponge, leaves, or wood. Animal and vegetal reigns trabecular materials exploit anisotropy and morphology, increasing their functional efficiency, not only placing material where most is needed to resist applied loads but also introducing the ability to promote and facilitate bone regeneration.

Modern medicine is taking advantage of continuous progress in biomedical engineering. This Special Issue is dedicated to presenting the most promising recent research advancements of new biomimetic hybrid materials, scaffolds and implants, and innovative biomechanical research approaches, as well as reviewing results from a broad category related to applications using biomimetic architected structures in metals, ceramics, polymers, and their combinations in nanocomposites and hybrid materials.

The bone tissue biomechanics topics to exploit include, but are not limited to, the use of targeted biomolecules, mechanical properties, multi-scale porous scaffolds involving both micro and macro porosities, new structural controlled rate bioresorbable scaffolds, and engineering aspects such as design and 3D-additive fabrication techniques outlining the convergence between clinical applications and biomedical engineering from the perspective of innovative materials science and technologies.

Dr. Raffaella Aversa
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomimetics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• bone tissue engineering
• biomechanically active scaffolds
• metal additive scaffold manufacturing
• structural bioresorbable materials
• architected metamaterials
• multiscale porous scaffolds
• bioactive coatings and membranes
• metallic smart biomaterials
• ceramic smart biomaterials
• polymeric smart biomaterials
• biomechanics
• biomimetics
• nanocomposites
• hybrid materials
• bioresorbable ceramics
• bioresorbable polymers
• bioresorbable metals
• polymer composites and nanomaterials
• ceramic–polymeric hybrid systems
• hybrid smart structures
• functional biocoatings
• new theoretical approaches for biomimetic material and prostheses
• bionic prostheses based on smart materials
• shape memory alloys