The Role of Surgery in Thoracic Cancers (Volume II)

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".

Deadline for manuscript submissions: closed (15 April 2024) | Viewed by 415

Special Issue Editors


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Guest Editor
Department of General Thoracic Surgery, Nara Medical University Hospital, 840 Shijo-Cho, Kashihara, Nara 634-8522, Japan
Interests: surgery; lung cancer; isolated tumor cell; circulating tumor cell
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Guest Editor
Department of Thoracic Surgery, Faculty of Medicine, Teikyo University School of Medicine, Tokyo 173-8605, Japan
Interests: lung cancer; surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This collection is the second edition of the Special Issue “The Role of Surgery in Thoracic Cancers ” (https://0-www-mdpi-com.brum.beds.ac.uk/journal/cancers/special_issues/surgery_thoracic).

Innovative systemic treatments, minimally invasive thoracic surgery approaches, and perioperative medicine have changed the role of surgery in the treatment of thoracic cancer. Thanks to advances in diagnostic imaging, pre-invasive and early-stage lung cancer can be detected, and minimally invasive approaches and innovative image-guided resection are actively used. Additionally, long-term survival from advanced and metastatic tumors has been ensured by multidisciplinary treatment. Since lung cancer is the most common chronic disease among thoracic cancers, complete oncological resection must be performed with a view to preserving lung tissue and maintaining lung function in preparation for future disease progression. Surgery may also be worthwhile if a relapse occurs or because of the palliative condition chosen. This Special Issue entitled “The Role of Surgery in Thoracic Cancers” discusses the current role and future prospects of surgery in thoracic cancer treatment.

Prof. Dr. Noriyoshi Sawabata
Dr. Yuichi Saito
Guest Editors

Manuscript Submission Information

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Keywords

  • thoracic cancer
  • thoracic surgery
  • systemic treatment
  • minimally invasive thoracic surgery
  • diagnostic imaging
  • image-guided resection
  • multidisciplinary treatment
  • palliative treatment

Published Papers (1 paper)

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Research

12 pages, 852 KiB  
Article
Perioperative Evaluation of the Physical Quality of Life of Patients with Non-Small Cell Lung Cancer: A Prospective Study
by Ryuta Fukai, Tomoki Nishida, Hideyasu Sugimoto, Makoto Hibino, Shigeto Horiuchi, Tetsuri Kondo, Shinichi Teshima, Masahiro Hirata, Keiko Asou, Etsuko Shimizu, Yuichi Saito and Yukinori Sakao
Cancers 2024, 16(8), 1527; https://0-doi-org.brum.beds.ac.uk/10.3390/cancers16081527 - 17 Apr 2024
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Abstract
Surgery is the most effective treatment for early-stage lung cancer; however, it poses a higher physical burden than other treatment options. Therefore, understanding the perioperative course of patients is important. Using the Short Form Health Survey 36, we prospectively measured the physical quality [...] Read more.
Surgery is the most effective treatment for early-stage lung cancer; however, it poses a higher physical burden than other treatment options. Therefore, understanding the perioperative course of patients is important. Using the Short Form Health Survey 36, we prospectively measured the physical quality of life of patients who underwent anatomical pulmonary resection for non-small cell lung cancer at Shonan Kamakura General Hospital, Kanagawa, Japan (n = 87). In the preoperative setting, patients who had lower performance status and lived alone had significantly worse physical quality of life scores on multivariate analysis (regression coefficient (95% confidence interval), −9.37 (−13.43–−5.32) and −10.22 (−13.74–−7.40), respectively, p < 0.0001 for both). At 6 months postoperatively, patients who stopped smoking within 1 year preoperatively (stopped smoking within 1 year vs. remote or never smokers, 41.0 ± 10.5 vs. 48.6 ± 7.2, p = 0.002), had lower performance status (0 vs. 1–2, 49.3 ± 6.6 vs. 38.6 ± 9.6, p < 0.0001), lived alone (living alone vs. living with somebody, 41.6 ± 9.7 vs. 48.1 ± 7.9, p = 0.021), and had higher comorbid burden (Charlson comorbidity index <3 vs. ≥3, 48.2 ± 6.9 vs. 39.1 ± 14.7, p = 0.003) had significantly worse physical quality of life scores on univariate analysis. More recent smoking (regression coefficient (95% confidence interval), −4.90 (−8.78–1.0), p = 0.014), lower performance status (8.90 (5.10–12.70), p < 0.0001), living alone (5.76 (1.39–10.13), p = 0.01), and higher comorbid burden (−6.94 (−11.78–−2.10), p = 0.006) were significant independent predictors of worse postoperative physical quality of life on multivariate analysis. Therefore, patients with these conditions might need additional support to maintain their physical condition after anatomical lung cancer surgery. Full article
(This article belongs to the Special Issue The Role of Surgery in Thoracic Cancers (Volume II))
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