Advances in Pharmacotherapeutic Strategies to Prevent Tumor Development, Progression and Treatment Resistance
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 401
Special Issue Editor
Interests: tumor microenvironment; cell–cell signaling; cell metabolism; hypoxia; oxidative stress; drug repurposing; ovarian cancer; breast cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Recent advances in our understanding of the molecular mechanisms underlying cancer progression have promoted the de novo development of novel small molecules and facilitated drug repositioning to complement contemporary therapeutic approaches to enhance patient survival. Pharmacotherapeutics that target nonredundant pathways in tumor cells required for proliferation, survival and unchecked self-renewal capacity have provided additional strategies to improve standard of care in treating many forms of cancer. Moreover, appreciating the importance of targeting the stromal compartment (e.g., immune cells, fibroblasts, adipocytes) has further exposed therapeutic liabilities in the tumor microenvironment that may present additional options to prevent tumor cell growth and suppress cancer cell resistance to therapeutics. Further identification and elaboration of necessary intracellular pathways and cell–cell signaling mechanisms may inform new pharmacotherapeutic approaches to prevent tumor development, progression, and treatment resistance to build on currently available clinical strategies.
This issue of Current Issues in Molecular Biology is open to both original research articles and review articles focused on the advances in our understanding of actionable mechanisms for pharmacologic exploitation to prevent cancer development and progression. Identifying and elaborating on these mechanisms may provide a path forward in improving patient care and outcomes.
Dr. Peter C. Hart
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer
- therapeutic resistance
- drug tolerance
- mechanisms of tumor development
- mechanisms of tumor progression
