Advances in the Diagnosis and Prevention of Sudden Death

Dear Colleagues,

Sudden death is an event that occurs instantaneously, with no apparent symptoms or in any case within a very short time from the onset of symptoms, occurring completely unexpectedly for time and modality. Sudden deaths can affect people of any age, from infants to young adults to the elderly, with high mortality and impact on public health. The vast majority of cases of sudden death are attributable to events with cardiac etiology, such as fatal arrhythmias, acute myocardial infarction, cardiomyopathies, although acute fatal events with neurogenic or respiratory etiology are also possible. Diagnosing and preventing sudden deaths is certainly a major challenge, both for the clinician and for the pathologist. On the patient, clinical cases can be varied, with very different clinical presentations or often overlooked family histories for these events. On cadavers, on the other hand, the literature estimates that a significant proportion of sudden deaths, which can be estimated at around 1/3 of the cases, do not show diriment signs at post-mortem examination or show findings only suggestive of sudden death with no macroscopic or microscopic pathognomonic evidence. This invalidates the correct diagnosis of these events, making it difficult to identify them even in the post-mortem. The purpose of this Special Issue is to deepen research in the field of diagnostics and prevention of sudden deaths both in the patient and cadaver through the introduction of new research approaches aimed at reducing the impact of these events on public health . To this end, papers from all branches related to the topic of sudden deaths are welcome, including:

• Forensic pathology;
• Emergency Medicine;
• Cardiology;
• Anesthesiology;
• Internal Medicine;
• Neurology
• Pneumology;
• Genetics;
• Molecular biology;
• Clinical biochemistry;
• Heart surgery;
• Forensic Medicine;
• Hygiene;
• Gastroenterology;
• Informatics.

Dr. Isabella Aquila
Dr. Matteo Antonio Sacco
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• diagnostics
• sudden death
• myocardial infarction
• prevention
• SIDS
• clinical investigations