The Contribution of Epigenetic Inheritance Processes in Learning and Memory

Dear Colleagues,

Experiences and different environmental factors can contribute to age-related cognitive decline and Alzheimer’s disease (AD). So far, it is well accepted that epigenetic modifications occurring during lifetime play an important role in the disease. On the other hand, little is known about the epigenetic inheritance of chronic diseases. Epigenetic inheritance refers to the transmission of several epigenetic marks to offspring, who inherit the phenotype in the absence of the external signal. Thus, the mechanisms underlying this transgenerational memory of the environment and its consequences on the successive generations remains unexplored and might involve several epigenetic mechanisms, contributing to the risk of chronic disease later in life on the successive generations. This Special Issue will be focused on those epigenetic changes from early life through to adulthood.

Dr. Christian Griñán-Ferré
Guest Editor

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• aging
• age-related
• epigenetics
• epigenetic inheritance
• learning and memory
• cognitive decline
• neuroscience