One Health Approach: State-of-the-Art on Fungal Infection in the Americas and the Caribbean

A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Pathogenesis and Disease Control".

Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 17954

Special Issue Editors


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Guest Editor
Mycotic Diseases Branch, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA, and Center of Expertise in Mycology Radboudumc/CWZ, Nijmegen, The Netherlands
Interests: laboratory diagnosis; epidemiology; HIV; infectious disease; histoplasmosis; Candida infections; endemic mycoses; emerging pathogents; public health

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Guest Editor
Mycotic Diseases Branch, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA
Interests: epidemiology; fungal diseases; public health; Coccidioides; Histoplasma; Blastomyces; Candida; Aspergillus; Mucormycetes; emerging infectious diseases
Special Issues, Collections and Topics in MDPI journals
Mycotic Diseases Branch, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA
Interests: zoonotic diseases; epidemiology; emerging pathogens; infectious disease; public health

Special Issue Information

Dear Colleagues,

We invite you to contribute to a Special Issue on the interconnection of human, animal, and environmental health in emerging and established fungal diseases of humans and animals. The One Health approach bridges silos and sectors, involving professionals of diverse backgrounds, including physicians, veterinarians, and a wide range of scientific specialties, on multiple levels, from local to global. Fungal diseases are well-suited to the One Health approach, yet such collaborations have been limited to date.

The fungal kingdom is estimated to contain millions of species, most still undescribed, and is the largest and most diverse of the kingdoms of life. Fungi are ubiquitous in the environment, although extremely diverse across environments, and are the primary cause of plant diseases. Although nearly all fungi either co-exist harmlessly or even beneficially with animals, an estimated 600 species can cause disease in humans. The One Health approach is increasingly important in recent years, as accelerating changes occur at the human, animal, and environmental interface. These changes have impacted the spread and frequency of fungal diseases and have also permitted the emergence or re-emergence of fungal pathogens.

The goal of this Special Issue is to describe fungal One Health issues, including fungal zoonosis and sapronoses (i.e., pathogens that are free-living in the environment) that affect or have the potential to affect human populations. Oomycetes (e.g., Pythium) and other fungal-like organisms will also be included. This issue will include reviews, original studies, and novel perspectives on animal–human and environment–human transmitted fungal diseases, environment-acquired antifungal resistance, and air–food–water safety.

Dr. Diego H. Caceres
Dr. Brendan R. Jackson
Dr. Karen Wu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • One Health
  • zoonosis
  • sapronoses
  • fungal infections
  • emerging pathogens

Published Papers (2 papers)

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Review

33 pages, 2147 KiB  
Review
Sporothrix brasiliensis: A Review of an Emerging South American Fungal Pathogen, Its Related Disease, Presentation and Spread in Argentina
by Alejandro Etchecopaz, María A. Toscanini, Amelia Gisbert, Javier Mas, Miguel Scarpa, Cristina A. Iovannitti, Karla Bendezú, Alejandro D. Nusblat, Ricardo Iachini and María L. Cuestas
J. Fungi 2021, 7(3), 170; https://0-doi-org.brum.beds.ac.uk/10.3390/jof7030170 - 26 Feb 2021
Cited by 63 | Viewed by 4349
Abstract
Sporotrichosis, caused by Sporothrix schenckii and related species, is the most frequent implantation mycosis in Latin America. In Argentina, over the last 8 years, there have been 0.16 new cases per month of feline sporotrichosis in 2011, increasing to 0.75 cases per month [...] Read more.
Sporotrichosis, caused by Sporothrix schenckii and related species, is the most frequent implantation mycosis in Latin America. In Argentina, over the last 8 years, there have been 0.16 new cases per month of feline sporotrichosis in 2011, increasing to 0.75 cases per month in 2019 and involving zoonotic transmission to humans. Molecular identification by polymerase chain reaction (PCR) detected Sporothrix brasiliensis in these feline and zoonotic outbreaks. This study will focus on different feline and human sporotrichosis outbreaks caused by S. brasiliensis in Argentina during 2011–2019. We will address the sources of infection and environmental hotspots, as well as the application of several treatment strategies for improving the pharmacotherapy of the different clinical forms of the disease. Finally, we will provide a detailed summary of the clinical aspects and new advances in host–pathogen interactions, virulence factors and immune response, focusing on state-of-the-art diagnostic tools and potential vaccine candidates. Full article
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26 pages, 1577 KiB  
Review
A One Health Approach to Combatting Sporothrix brasiliensis: Narrative Review of an Emerging Zoonotic Fungal Pathogen in South America
by John A. Rossow, Flavio Queiroz-Telles, Diego H. Caceres, Karlyn D. Beer, Brendan R. Jackson, Jose Guillermo Pereira, Isabella Dib Ferreira Gremião and Sandro Antonio Pereira
J. Fungi 2020, 6(4), 247; https://0-doi-org.brum.beds.ac.uk/10.3390/jof6040247 - 26 Oct 2020
Cited by 65 | Viewed by 12998
Abstract
Cat-transmitted sporotrichosis caused by Sporothrix brasiliensis has become a major public health concern and presents a distinct divergence from the traditional epidemiology of sporotrichosis. This emerging fungal pathogen spreads readily among cat populations, and human infections occur exclusively via zoonotic transmission. While sporotrichosis [...] Read more.
Cat-transmitted sporotrichosis caused by Sporothrix brasiliensis has become a major public health concern and presents a distinct divergence from the traditional epidemiology of sporotrichosis. This emerging fungal pathogen spreads readily among cat populations, and human infections occur exclusively via zoonotic transmission. While sporotrichosis is an implantation mycosis that typically manifests as cutaneous lesions in humans and cats, severe extracutaneous manifestations are more common with S. brasiliensis than other Sporothrix species infections. Rapid diagnosis and appropriate treatment regimens are critical for successful clinical resolution of sporotrichosis in both cats and humans. Species-level identification of Sporothrix is possible with molecular diagnostics and necessary for tracking the geographic expansion of S. brasiliensis and better understanding its epidemiology. Combatting cat-transmitted sporotrichosis requires a One Health approach to successfully implement public health control measures. Full article
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