Journal of Personalized Medicine

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Special Issue Editors

Dr. Giuseppe La Rocca

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Guest Editor

1. Unit of Neurosurgery, Mater Olbia Hospital, 07026 Olbia, Italy
2. Institute of Neurosurgery, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Catholic University, 00168 Rome, Italy
Interests: degenerative spine; traumatic spine; spine tumor; spine surgery
Special Issues, Collections and Topics in MDPI journals

Dr. Brian Perri

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Co-Guest Editor

1. DOCS Surgical Hospital and DOCS Health, Los Angeles, CA, USA
2. Spine Surgery Cedars Sinai Medical Center, Los Angeles, CA, USA
Interests: cervical and lumbar artificial disc replacement surgery (ADR); degenerative disc disease; reconstructive surgery for spinal tumors and deformities

Special Issue Information

Dear Colleagues,

Diagnostic imaging in spine disease is of paramount importance today, and it includes an understanding of the pathology, its gravity, and influence on life, as well as the psychosocial background. Hence, appropriate management plan is crucial in diagnostic imaging.

Moreover, the constant technological developments have kept providing new updates to diagnostic imaging, with improved imaging visualization and more detailed images allowing a more sophisticated diagnosis and, ultimately, the best therapeutic strategy for the patient.

Spinal surgery sees the benefits of this tremendous technological innovation both in diagnosis and intraoperative imaging and/or navigation tools.

The goal of this Special Issue of the Journal of Personalized Medicine, “Diagnostic Imaging of Spine Disease”, is to publish new and interesting studies, particularly original research with a clinical focus.

Dr. Giuseppe La Rocca
Dr. Brian Perri
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

degenerative spine
spine disease
diagnostic spine images
spine surgery
technology in spine
3D imaging in spine

Published Papers (2 papers)

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Research

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11 pages, 1498 KiB

Open AccessArticle

Cone-Beam Navigation Can Reduce the Radiation Exposure and Save Fusion Length-Dependent Operation Time in Comparison to Conventional Fluoroscopy in Pedicle-Screw-Based Lumbar Interbody Fusion

by Sebastian Rohe, Patrick Strube, Alexander Hölzl, Sabrina Böhle, Timo Zippelius and Chris Lindemann

J. Pers. Med. 2022, 12(5), 736; https://0-doi-org.brum.beds.ac.uk/10.3390/jpm12050736 - 1 May 2022

Viewed by 1554

Abstract

This study investigates the advantages and disadvantages of cone-beam-based navigated standardized posterior lumbar interbody fusion surgery (PLIF), regarding the radiation exposure and perioperative time management, compared to the use of fluoroscopy. Patients treated receiving an elective one- to three-level PLIF were retrospectively enrolled in the study. The surgery time, preparation time, operation room time, and effective dose (mSv) were analyzed for comparison of the radiation exposure and time consumption between cone-beam and fluoroscopy; Results: 214 patients were included (108 cone-beam navigated, and 106 traditional fluoroscopies). Using cone-beam navigation, reductions in the effective dose (2.23 ± 1.96 mSv vs. 3.39 ± 2.32 mSv, p = 0.002) and mean surgery time of 30 min (143.62 ± 43.87 min vs. 171.10 ± 48.91 min, p < 0.001) were demonstrated, which leveled out the extended preparation time of 7–8 min (37.25 ± 9.99 min vs. 29.65 ± 7.69 min, p < 0.001). These effects were fusion length dependent and demonstrated additional benefits in multisegmental surgeries. The cone-beam navigation system led to a reduction in the perioperative time requirements and radiation exposure. Furthermore, the controversially discussed longer preparation time when using cone-beam navigation was amortized by a shortened surgery time, especially in multilevel surgery. Full article

(This article belongs to the Special Issue Diagnostic Imaging and Minimally Invasive Treatment of Degenerative Spine Disease)

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Review

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14 pages, 2575 KiB

Open AccessReview

Degenerative Disc Disease of the Spine: From Anatomy to Pathophysiology and Radiological Appearance, with Morphological and Functional Considerations

by Luca Scarcia, Marco Pileggi, Arianna Camilli, Andrea Romi, Andrea Bartolo, Francesca Giubbolini, Iacopo Valente, Giuseppe Garignano, Francesco D’Argento, Alessandro Pedicelli and Andrea Maria Alexandre

J. Pers. Med. 2022, 12(11), 1810; https://0-doi-org.brum.beds.ac.uk/10.3390/jpm12111810 - 1 Nov 2022

Cited by 7 | Viewed by 6182

Abstract

Degenerative disc disease is a common manifestation in routine imaging of the spine; this finding is partly attributable to physiological aging and partly to a pathological condition, and sometimes this distinction is simply not clear. In this review, we start focusing on disc anatomy and pathophysiology and try to correlate them with radiological aspects. Furthermore, there is a special focus on degenerative disc disease terminology, and, finally, some considerations regarding disc morphology and its specific function, as well as the way in which these aspects change in degenerative disease. Radiologists, clinicians and spine surgeons should be familiar with these aspects since they have an impact on everyday clinical practice. Full article

(This article belongs to the Special Issue Diagnostic Imaging and Minimally Invasive Treatment of Degenerative Spine Disease)

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