Hepatic Nuclear Receptors in Liver Pathologies
A special issue of Medicina (ISSN 1648-9144).
Deadline for manuscript submissions: closed (1 April 2022) | Viewed by 273
Special Issue Editor
Special Issue Information
Dear Colleagues,
We will be publishing a Special Issue on the Hepatic Nuclear Receptors in Liver Health and Disease. Nuclear receptors are a family of ligand-activated transcription factors and have been implicated in multiple biological pathways. Many hepatic nuclear receptors regulate both parenchymal and non-parenchymal cell functions to integrate glucose, lipid and bile acid homeostasis. Particularly, recent advances in multi-omics analyses have provided a comprehensive image of these nuclear receptor functions in health and disease states in the liver. In this Special Issue, we aim to review recent discoveries in hepatic nuclear receptor functions under normal physiology as well as pathological conditions, such as alcoholic liver disease, nonalcoholic steatohepatitis, hepatic fibrosis, cholestasis, and liver cancer. We welcome submissions of review articles on key hepatic nuclear receptor functions, such as HNF4A, PPARA, LXR, FXR, SHP, CAR/PXR, GR, and VDR.
Dr. Kang-ho Kim
Guest Editor
Manuscript Submission Information
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Keywords
- nuclear receptor
- liver
- metabolism
- glucose
- lipid
- bile acid
- steatohepatitis
- hepatic fibrosis
- liver cancer
