Dear Colleagues,

Over the last few decades, there has been significant progress made towards our understanding of the mechanisms of brain functions and their role in neurological diseases. Among various neuro-technological tools contributing to this progress, brain–machine interfaces (BMIs) with implantable neural microsystems have played a key role by enabling the stimulation and detection of neural activity at unprecedented spatio-temporal resolution from animals. Moreover, recent human clinical trials have extended the potential applications of implantable neural microsystems to the territory of human health. Through this Special Issue, we would like to establish a forum to discuss the recent developments, remaining challenges, and future directions of implantable neural microsystems for brain–machine interfaces.

We invite research papers, reviews, and shorter communications that focus on the system design, materials, device fabrication, packaging, and characterization of implantable neural microsystems to contribute to this Special Issue. Topics of particular interest include, but are not limited to:

• Implantable ultra-high-density or 3D multi-electrode arrays (MEAs)
• Multi-modal neural probes and sensors/stimulators
• Flexible or deformable neural probes
• Ultra-low-power systems-on-a-chip (SoCs) for neural sensing and stimulation
• Ultra-high-density neural sensing/stimulating microsystems
• Distributed neural sensing/stimulating microdevices
• Energy delivery/harvesting and neural data transmission strategies
• Microsystem integration technologies
• Encapsulation materials and techniques
• Long-term reliability of implantable microsystems
• Implantable microsystems for peripheral nerve systems
• Alternative applications of implantable neural microsystems (e.g., sensory prosthetics)
• Behavioral study in animals with implantable neural microsystems
• Preclinical and clinical trials of implantable neural microsystems

Prof. Dr. Yoon-Kyu Song
Guest Editor

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