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Micromachines
Special Issues
Nano-Bio Optical Devices and Applications
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Nano-Bio Optical Devices and Applications

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".

Deadline for manuscript submissions: closed (10 February 2022) | Viewed by 3021

Special Issue Editor

Dr. Brian Vohnsen

E-Mail Website
Guest Editor
Advanced Optical Imaging Group, School of Physics, University College Dublin, Dublin D04, Ireland
Interests: nano-optics; biophotonics; imaging; microscopy; ophthalmology; adaptive optics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nanoscience, biology, and biotechnology are increasingly being combined into a single field of nano-bio science in order to find novel solutions to combat global problems and enhance quality of life. This interdisciplinary field combines elements of physics, chemistry, engineering optics, and photonics with biology and health sciences. Examples include novel nanostructured materials for disease screening, drug delivery, wearable health monitors, solar cells, display technology, biomimicry, quantum engineering, molecular modelling, environmental improvement, and artificial intelligence. This Special Issue seeks contributions that showcase original research papers, short communications, and review articles that describe the recent progress in the area of nano-bio science for sensors, imaging, or diagnostics.

Prof. Dr. Brian Vohnsen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Nanobiotechnology
  • Biomimicry
  • Imaging
  • Molecular Modelling
  • Health

Published Papers (1 paper)

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Research

12 pages, 3174 KiB  
Article
Optical Projection Tomography Using a Commercial Microfluidic System
by Wenhao Du, Cheng Fei, Junliang Liu, Yongfu Li, Zhaojun Liu, Xian Zhao and Jiaxiong Fang
Micromachines 2020, 11(3), 293; https://0-doi-org.brum.beds.ac.uk/10.3390/mi11030293 - 11 Mar 2020
Cited by 7 | Viewed by 2467
Abstract
Optical projection tomography (OPT) is the direct optical equivalent of X-ray computed tomography (CT). To obtain a larger depth of field, traditional OPT usually decreases the numerical aperture (NA) of the objective lens to decrease the resolution of the image. So, there is [...] Read more.
Optical projection tomography (OPT) is the direct optical equivalent of X-ray computed tomography (CT). To obtain a larger depth of field, traditional OPT usually decreases the numerical aperture (NA) of the objective lens to decrease the resolution of the image. So, there is a trade-off between sample size and resolution. Commercial microfluidic systems can observe a sample in flow mode. In this paper, an OPT instrument is constructed to observe samples. The OPT instrument is combined with commercial microfluidic systems to obtain a three-dimensional and time (3D + T)/four-dimensional (4D) video of the sample. “Focal plane scanning” is also used to increase the images’ depth of field. A series of two-dimensional (2D) images in different focal planes was observed and compared with images simulated using our program. Our work dynamically monitors 3D OPT images. Commercial microfluidic systems simulate blood flow, which has potential application in blood monitoring and intelligent drug delivery platforms. We design an OPT adaptor to perform OPT on a commercial wide-field inverted microscope (Olympusix81). Images in different focal planes are observed and analyzed. Using a commercial microfluidic system, a video is also acquired to record motion pictures of samples at different flow rates. To our knowledge, this is the first time an OPT setup has been combined with a microfluidic system. Full article
(This article belongs to the Special Issue Nano-Bio Optical Devices and Applications)
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