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Special Issue Information

Dear Colleagues,

In recent years, significant advancements have been witnessed in the material design for chemical sensing and biosensing. On the one hand, material chemists have developed innovative synthetic methods by understanding the structure-property of materials at molecular level. A wide variety of nanostructures such as nanosheets, nanodots, nanotubes, nanowires, nanoarrays, nanoribbons, and core-shell nanostructures have been reported. On the other hand, analytical chemists have developed a variety of engineering designs that have the potential to transform conventional centralized laboratory-based assays into decentralized, mobile point-of-care (POC) devices. Notable among them are paper-based devices, microfluidics, smartphone integration, multiplexed sensors, microneedles, magnetic skins, and wearable sensors. In terms of materials, two-dimensional layered materials, metal-organic frameworks, perovskites, carbon dots, quantum dots and ternary metal/metal oxides are some of the key players. Overall, material science and sensing technology have made significant progress individually, which ultimately enhances the biosensor outcome collectively. This Special Issue, entitled “Recent Advances of Nanomaterials for Chemical Sensors and Biosensors”, aims to collect original articles and reviews on the latest developments of nanomaterials focused on chemical sensors and biosensors.

Dr. Veerappan Mani
Guest Editor

Manuscript Submission Information

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Keywords

Nanomaterials
Chemical sensors
Biosensors
Carbon nanomaterials
Metal nanoparticles
2D layered materials
Metal dichalcogenides
Organic nanomaterials
Electrochemical
Fluorescence
Chemiluminescence
Microfluidics
Point-of-care

Published Papers (2 papers)

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Research

Jump to: Review

11 pages, 2578 KiB

Open AccessArticle

Assessing Hemorrhagic Shock Severity Using the Second Heart Sound Determined from Phonocardiogram: A Novel Approach

by Yan Chen, Aisheng Hou, Xiaodong Wu, Ting Cong, Zhikang Zhou, Youyou Jiao, Yungen Luo, Yuheng Wang, Weidong Mi and Jiangbei Cao

Micromachines 2022, 13(7), 1027; https://0-doi-org.brum.beds.ac.uk/10.3390/mi13071027 - 28 Jun 2022

Cited by 1 | Viewed by 1491

Abstract

Introduction: Hemorrhagic shock (HS) is a severe medical emergency. Early diagnosis of HS is important for clinical treatment. In this paper, we report a flexible material-based heart sound monitoring device which can evaluate the degree of HS through a phonocardiogram (PCG) change. Methods: Progressive hemorrhage treatments (H1, H2, and H3 stage) were used in swine to build animal models. The PCG sensor was mounted on the chest of the swine. Routine monitoring was used at the same time. Results: This study showed that arterial blood pressure decreased significantly from the H1 phase, while second heart sound amplitude (S2A) and energy (S2E) decreased significantly from the H2 phase. Both S2A and S2E correlated well with BP (p < 0.001). The heart rate, pulse pressure variation and serum hemoglobin level significantly changed in the H3 stage (p < 0.05). Discussion: The change of second heart sound (S2) was at the H2 stage and was earlier than routine monitoring methods. Therefore, PCG change may be a new indicator for the early detection of HS severity. Full article

(This article belongs to the Special Issue Recent Advances of Nanomaterials for Biosensors)

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Review

Jump to: Research

20 pages, 4437 KiB

Open AccessReview

Recent Advances in Cochlear Implant Electrode Array Design Parameters

by Yavuz Nuri Ertas, Derya Ozpolat, Saime Nur Karasu and Nureddin Ashammakhi

Micromachines 2022, 13(7), 1081; https://0-doi-org.brum.beds.ac.uk/10.3390/mi13071081 - 08 Jul 2022

Cited by 15 | Viewed by 8207

Abstract

Cochlear implants are neural implant devices that aim to restore hearing in patients with severe sensorineural hearing impairment. Here, the main goal is to successfully place the electrode array in the cochlea to stimulate the auditory nerves through bypassing damaged hair cells. Several electrode and electrode array parameters affect the success of this technique, but, undoubtedly, the most important one is related to electrodes, which are used for nerve stimulation. In this paper, we provide a comprehensive resource on the electrodes currently being used in cochlear implant devices. Electrode materials, shape, and the effect of spacing between electrodes on the stimulation, stiffness, and flexibility of electrode-carrying arrays are discussed. The use of sensors and the electrical, mechanical, and electrochemical properties of electrode arrays are examined. A large library of preferred electrodes is reviewed, and recent progress in electrode design parameters is analyzed. Finally, the limitations and challenges of the current technology are discussed along with a proposal of future directions in the field. Full article

(This article belongs to the Special Issue Recent Advances of Nanomaterials for Biosensors)

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