Advances in Human Rhinovirus Infections

Dear Colleagues,

Human rhinovirus, a genus of the family Picornaviridae, is small and non-enveloped. It is the main cause of acute upper and lower respiratory tract infections (RTIs) among all age groups. Manifestations of rhinovirus infection include pneumonia, exacerbations of asthma and chronic obstructive pulmonary disease, otitis media, and sinusitis. Molecular biology methods have allowed to identify rhinovirus and understand the pathogenic mechanism of this pathogen in RTIs. Rhinovirus is extremely antigenically diverse in structure, with over 150 different serotypes/strains, grouped into three categories, A, B, and C. Hence, the patient's immunity to rhinovirus after infection is often considered serotype-specific. A person can have multiple episodes of infection caused by different strains of rhinovirus, especially in children. Although studies have been conducted for more than 50 years, no effective antiviral drugs or vaccines have been approved against this common pathogen.

In this Special Issue of Microorganisms, we aim to collect original papers or reviews that contribute to an improved understanding of the structure, classification, epidemiology, infection, clinical diagnosis, treatment, and immunopathology of the rhinovirus. We are also very interested in reports on the development of vaccines or antiviral agents against rhinovirus infections.

Prof. Dr. Philippe Colson
Dr. Van Thuan Hoang
Guest Editors

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• human rhinovirus
• immunity
• vaccine
• infection
• immunopathology
• epidemiology
• clinical microbiology