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Microorganisms
Special Issues
Antimicrobial Resistance: Challenges and Innovative Solutions
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Antimicrobial Resistance: Challenges and Innovative Solutions

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 938

Special Issue Editor

Dr. Dimitris C. Chatzopoulos

E-Mail Website
Guest Editor
Department of Public and One Health, University of Thessaly, Volos, Greece
Interests: zoonoses; antimicrobial resistance; molecular epidemiology; biofilm production; emerging pathogens

Special Issue Information

Dear Colleagues,

Microorganisms invites researchers to contribute to a Special Issue addressing the critical issue of antimicrobial resistance. This Special Issue aims to explore the challenges posed by antimicrobial resistance and highlight innovative solutions to combat this global threat.

We welcome original research, reviews, and perspectives on various aspects of antimicrobial resistance, including mechanisms of resistance, epidemiology, and the impact on human and animal health. Contributions investigating novel therapeutic approaches such as combination therapies, alternative antimicrobial agents, and drug repurposing are encouraged.

Additionally, we invite the submission of studies on antimicrobial stewardship programs, infection control strategies, and surveillance systems aimed at monitoring and preventing the spread of resistant pathogens. Research on the development of diagnostic tools, vaccines, and strategies to mitigate the emergence and dissemination of resistance genes will also be highly valued.

Dr. Dimitris C. Chatzopoulos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial resistance
  • mechanisms of resistance
  • therapeutic approaches
  • antimicrobial stewardship
  • infection control
  • public health

Published Papers (1 paper)

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Research

11 pages, 610 KiB  
Article
Impact of Multidrug-Resistant Organisms on Severe Acquired Brain Injury Rehabilitation: An Observational Study
by Giovanna Barbara Castellani, Elisa Maietti, Valentina Colombo, Stefano Clemente, Ivo Cassani and Paola Rucci
Microorganisms 2024, 12(4), 830; https://0-doi-org.brum.beds.ac.uk/10.3390/microorganisms12040830 - 19 Apr 2024
Viewed by 236
Abstract
Healthcare-associated infections (HAIa) and antimicrobial resistance are expected to be the next threat to human health and are most frequent in people with severe acquired brain injury (SABI), who can be more easily colonized by multidrug-resistant organisms (MDROs). The study’s aim is to [...] Read more.
Healthcare-associated infections (HAIa) and antimicrobial resistance are expected to be the next threat to human health and are most frequent in people with severe acquired brain injury (SABI), who can be more easily colonized by multidrug-resistant organisms (MDROs). The study’s aim is to investigate the impact of MDRO colonizations and infections on SABI rehabilitation outcomes. This retrospective observational study was performed in a tertiary referral specialized rehabilitation hospital. The main outcomes were the presence of carbapenemase-producing Enterobacteriaceae (CPE) colonization, type and timing of HAI and MDRO HAI, and the number of CPE transmissions. We included 48 patients, 31% carrying CPE on admission and 33% colonized during the hospitalization. A total of 101 HAI were identified in 40 patients, with an overall incidence of 10.5/1000 patient days. Some 37% of patients had at least one MDRO infection, with a MDRO infection incidence of 2.8/1000 patient days. The number of HAIs was significantly correlated with the length of stay (LOS) (r = 0.453, p = 0.001). A significant correlation was found between colonization and type of hospital room (p = 0.013). Complications and HAI significantly affected LOS. We suggest that CPE carriers might be at risk of HAI and worse outcomes compared with non-CPE carriers. Full article
(This article belongs to the Special Issue Antimicrobial Resistance: Challenges and Innovative Solutions)
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