Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
6.4
4.5
Journals
Microorganisms
Special Issues
Gut Microbiome and Nutrients: The Two Variables, Determining Factors for...
share announcement

Gut Microbiome and Nutrients: The Two Variables, Determining Factors for Human Traits and Diseases

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 4858

Special Issue Editor

Dr. Seong-Tshool Hong

E-Mail Website
Guest Editor
Department of Biomedical Sciences and Institute for Medical Science, School of Medicine, Chonbuk National University, Jeonju, Republic of Korea
Interests: gut microbiome; trait; disease; nutrient; gene; composition of the gut microbiome
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The gut microbiome has opened a new horizon for biological science by showing that the gut microbiome contributes significantly to the traits of humans and diseases as much as genes. The etiological role of the gut microbiome has been shown with atherosclerosis, hypertension, obesity, diabetes, metabolic syndrome, inflammatory bowel disease, gastrointestinal tract malignancies, hepatic encephalopathy, allergies, migraines, autism, neurological diseases, psychological diseases, etc. Alteration of the gut microbial composition even affects behavior, intelligence, mood, and other psychological traits of the hosts through the gut–brain axis.

In the gut, the growth of each bacterium is primarily determined by nutrients, suggesting them as the main determining factors for the composition of the gut microbiome. Considering microbes’ dependency on specific nutrients, the gut microbiota could be the missing link between nutrients and human traits. Thus, the effect of nutrients on human traits and diseases would be the combined results from the nutrients and the gut microbiome.

The aim of this Special Issue is to gather more information on the gut microbiome and nutrients. We would like to invite researchers to submit their research or review articles on the gut microbiome and nutrients concerning various aspects.

Dr. Seong-Tshool Hong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Gut microbiome
  • Trait
  • Disease
  • Nutrient
  • Gene
  • Composition of the gut microbiome

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

17 pages, 7217 KiB  
Article
Host Factors Affect the Gut Microbiome More Significantly than Diet Shift
by Enkhchimeg Lkhagva, Hea-Jong Chung, Ji-Seon Ahn and Seong-Tshool Hong
Microorganisms 2021, 9(12), 2520; https://0-doi-org.brum.beds.ac.uk/10.3390/microorganisms9122520 - 06 Dec 2021
Cited by 9 | Viewed by 4255
Abstract
The determining factors of the composition of the gut microbiome are one of the main interests in current science. In this work, we compared the effect of diet shift (DS) from heavily relying on meatatarian diets to vegetarian diets and physical exercise (EX) [...] Read more.
The determining factors of the composition of the gut microbiome are one of the main interests in current science. In this work, we compared the effect of diet shift (DS) from heavily relying on meatatarian diets to vegetarian diets and physical exercise (EX) on the composition of the gut microbiome after 3 months. Although both DS and EX affected the composition of the gut microbiome, the patterns of alteration were different. The α-diversity analyzed by InvSimpson, Shannon, Simpson, and Evenness showed that both EX and DS affected the microbiome, causing it to become more diverse, but EX affected the gut microbiome more significantly than DS. The β-diversity analyses indicated that EX and DS modified the gut microbiome in two different directions. Co-occurrence network analysis confirmed that both EX and DS modified the gut microbiome in different directions, although EX modified the gut microbiome more significantly. Most notably, the abundance of Dialister succinatiphilus was upregulated by EX, and the abundances of Bacteroides fragilis, Phascolarctobacterium faecium, and Megasphaera elsdenii were downregulated by both EX and DS. Overall, EX modulated the composition of the gut microbiome more significantly than DS, meaning that host factors are more important in determining the gut microbiome than diets. This work also provides a new theoretical basis for why physical exercise is more health-beneficial than vegetarian diets. Full article
(This article belongs to the Special Issue Gut Microbiome and Nutrients: The Two Variables, Determining Factors for Human Traits and Diseases)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop