Viral Infections Acquired in Pregnancy and through Breastfeeding: Novel Approaches to an Old Paradigm 2.0

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 10003

Special Issue Editor


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Guest Editor
Department of Infectious Diseases, University College Dublin, Dublin, Ireland
Interests: infectious diseases; tickborne infections; congenital lyme and infections in pregnancy; travel and tropical medicine, blood borne infections (HBV, HCV)
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Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our previous special issue "Viral Infections Acquired in Pregnancy and through Breastfeeding: Novel Approaches to an Old Paradigm".

Infections in pregnancy and during breastfeeding have traditionally been under-investigated and under-reported in the medical scientific literature. There are large gaps in the understanding of many facets of viral infections in pregnancy including pathogenesis, vertical transmission, severity, therapy, and immunization. A triad of factors—mother, infant, and placenta—is intricately related and poorly characterised. There is a paucity of data in the medical literature on the treatment of these infections due to the near systematic exclusion of pregnant and breastfeeding women from medical trials due to a fear of complications. This creates a lack of knowledge on pregnant women and unborn and recently born children and results in clinicians using therapies that may be below the standard of care or uncharacterised due to a lack of data.

This paradigm in clinical trial research is shifting, and attitudes towards the inclusion of pregnant woman in research are changing, for example, new data on vaccinations in dengue fever and zika have been published. For this Special Issue of Microorganisms, we invite authors to submit original research papers, case series, and reviews of current literature on all aspects of viral infections in pregnancy and breastfeeding. Papers on all relevant categories are welcome including blood-borne viruses, HIV, hepatitis, and vector borne infections like dengue fever, zika, tick borne encephalitis, West Nile virus, and Japanese encephalitis. We also welcome submissions on pandemic and seasonal viral infections like influenza, enteroviruses and COVID-19 and TORCH related viruses, such as CMV, HSV, VZV, and parvovirus. This list is in no way exhaustive, and interesting cases of lesser described viral infections are welcome.

I believe this is the time to concentrate on and describe the current landscape of research on viral infections in pregnancy and breastfeeding. We aim to create a forum to describe novel ways to foster a better understanding of manifestations in pregnancy, treatment in pregnancy, and how we should embrace new research initiatives for this very critical neglected population.

Dr. John Lambert
Guest Editor

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Published Papers (1 paper)

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Review

19 pages, 835 KiB  
Review
Human Papillomavirus Infection during Pregnancy and Childhood: A Comprehensive Review
by Ali Ardekani, Erfan Taherifard, Abolfazl Mollalo, Emadeddin Hemadi, Amirhossein Roshanshad, Reza Fereidooni, Safoura Rouholamin, Mahroo Rezaeinejad, Maryam Farid-Mojtahedi, Maryam Razavi and Ali Rostami
Microorganisms 2022, 10(10), 1932; https://0-doi-org.brum.beds.ac.uk/10.3390/microorganisms10101932 - 28 Sep 2022
Cited by 5 | Viewed by 9534
Abstract
Human papillomavirus (HPV), the most prevalent sexually transmitted disease worldwide, is the causative agent for several genital and oropharyngeal cancers and a suspected agent for many malignancies. HPV is associated with several adverse health outcomes during pregnancy. Infants are also at risk of [...] Read more.
Human papillomavirus (HPV), the most prevalent sexually transmitted disease worldwide, is the causative agent for several genital and oropharyngeal cancers and a suspected agent for many malignancies. HPV is associated with several adverse health outcomes during pregnancy. Infants are also at risk of HPV infection via different transmission routes: vertically from an infected mother and horizontally through sexual or non-sexual contact with infected individuals. Several HPV manifestations have been identified during childhood, ranging from common skin infections to severe complications such as juvenile recurrent respiratory papillomatosis. This review aims to provide a comprehensive overview of the epidemiology, manifestations, and treatment strategies of HPV infection during pregnancy and childhood. Moreover, we underline the role of vaccination in preventing complications. Full article
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