Special Issue "Micro/Nano Emulsions: Fabrication and Applications"

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Synthesis, Interfaces and Nanostructures".

Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 1283

Special Issue Editors

Prof. Dr. Gemma Gutierrez
E-Mail Website
Guest Editor
Department of Chemical and Environmental Engineering, University of Oviedo, Oviedo, Spain
Interests: emulsions; emulsification techniques; encapsulation; hydrophobicity; colloidal vesicles; colloidal complexes; novel emulsifiers; physicochemical stability
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Maria Matos
E-Mail Website
Guest Editor
Department of Chemical and Environmental Engineering, University of Oviedo, Oviedo, Spain
Interests: surfactants; contact angle; surface tension; emulsions; colloid chemistry; colloid dispersion; dynamic light scattering; particle size analysis; rheology; colloids
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to describe the techniques essential to producing microemulsions and nanoemulsions, taking into account novel formulations and novel preparation methods.

Articles submitted for publication in this Special Issue should be focused on microemulsion and nanoemulsion applications, such as drug delivery, encapsulation, and the synthesis of nanoparticles/nanostructured materials. We also welcome articles on preparation methods, innovative formulations, and the characterization of emulsions.

Articles could describe different formulations, such as formulations stabilized with surfactants, polymers, proteins, or other food-based particles, being of special interest those that allow for the droplet size and the droplet size distribution to be controlled or those with a low energy requirement.

Moreover, we welcome articles that describe any novel emulsion formulation regarding the final application or the use of novel grade stabilizers.

Prof. Dr. Gemma Gutierrez
Prof. Dr. Maria Matos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microemulsions
  • nanoencapsulation
  • particle formation
  • drug delivery

Published Papers (2 papers)

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Research

Article
Hypolipidemic Activity of Olive Oil-Based Nanostructured Lipid Carrier Containing Atorvastatin
Nanomaterials 2022, 12(13), 2160; https://0-doi-org.brum.beds.ac.uk/10.3390/nano12132160 - 23 Jun 2022
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Abstract
Currently, hyperlipidemia is a growing health issue that is considered a risk factor for obesity. Controlling body weight and modifying life style in most of cases are not adequate and the condition requires medical treatment. Statin drugs (mainly Atorvastatin (ATO)), have been used [...] Read more.
Currently, hyperlipidemia is a growing health issue that is considered a risk factor for obesity. Controlling body weight and modifying life style in most of cases are not adequate and the condition requires medical treatment. Statin drugs (mainly Atorvastatin (ATO)), have been used broadly and for long time as medications for handling higher levels of lipid, especially bad cholesterol, which accordingly controls the prevalence of obesity. Still, the obstacle that stands in front of any formulation is the poor solubility of the drug. Low solubility of ATO came up with poor absorption as well as poor bioavailability. This paved the way for the present study, which aimed to exploit nanotechnology and develop certain nanolipid carriers that could accommodate hydrophobic drugs, such as ATO. Nanostructured lipid carrier (NLC) containing ATO was fabricated using olive oil. Olive oil is natural plant oil possessing confirmed hypolipidemic activity that would help in improving the efficacy of the formulation. Via applying the Quality by Design (QbD) approach, one NLC formula was selected to be optimized based on appropriate size and higher entrapment. Optimized ATO-NLC was scrutinized for zeta potential, in vitro study and kinetic profile. Moreover, stability testing and in vivo hypolipidemic behavior was conducted. The optimized NLC formulation seemed to show particle size (254.23 nm) with neutral zeta potential (−1.77 mV) and entrapment efficiency (69.56%). The formulation could be prolonged for 12 h and provided higher % of release (97.17%). Stability testing confirmed the role of modifying the surface of the formulation with PEG-DSPE in providing a highly stable formulation that could withstand three months storage in two altered conditions. Ultimately, optimized ATO-NLC could successfully lower total cholesterol level in rats induced with obesity and fed a high-fat diet. Remarkably, ATO-NLC prepared with olive oil, in addition to shielding its surface, would provide a stable formulation that holds up the synergistic action between olive oil and ATO. Full article
(This article belongs to the Special Issue Micro/Nano Emulsions: Fabrication and Applications)
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Article
Morphological Studies of Composite Spin [email protected]2 Nanoparticles
Nanomaterials 2021, 11(12), 3169; https://0-doi-org.brum.beds.ac.uk/10.3390/nano11123169 - 23 Nov 2021
Cited by 2 | Viewed by 591
Abstract
Spin crossover (SCO) iron (II) 1,2,4-triazole-based coordination compounds in the form of composite [email protected]2 nanoparticles were prepared using a reverse microemulsion technique. The thickness of the silica shell and the morphology of the as obtained [email protected] nanoparticles were studied by modifying the [...] Read more.
Spin crossover (SCO) iron (II) 1,2,4-triazole-based coordination compounds in the form of composite [email protected]2 nanoparticles were prepared using a reverse microemulsion technique. The thickness of the silica shell and the morphology of the as obtained [email protected] nanoparticles were studied by modifying the polar phase/surfactant ratio (ω), as well as the quantity and the insertion phase (organic, aqueous and micellar phases) of the tetraethylorthosilicate (TEOS) precursor, the quantity of ammonia and the reaction temperature. The morphology of the nanoparticles was monitored by transmission electron microscopy (TEM/HRTEM) while their composition probed by combined elemental analyses, thermogravimetry and EDX analyses. We report that not only the particle size can be controlled but also the size of the silica shell, allowing for interesting perspectives in post-synthetic modification of the shell. The evolution of the spin crossover properties associated with the change in morphology was investigated by variable temperature optical and magnetic measurements. Full article
(This article belongs to the Special Issue Micro/Nano Emulsions: Fabrication and Applications)
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