Super-resolution Microscopy and Nanoscience

A special issue of Nanomaterials (ISSN 2079-4991).

Deadline for manuscript submissions: closed (12 March 2023) | Viewed by 3411

Special Issue Editor


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Guest Editor
School of Allied Health and Life Sciences, St Mary’s University, Twickenham, London, UK
Interests: nanorheology; soft matter; nanomechanics; nanobiophysics; nanotopography; atomic force microscopy; atomic force spectroscopy; Raman spectroscopy
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Special Issue Information

Dear Colleagues,

Super-resolution microscopy, also known as nanoscopy, is an umbrella term which encompasses all the optical microscopy techniques that are capable of going beyond the diffraction limit of optical microscopes and obtaining clear and highly resolved images of specimens with dimensions below 200 nm. The technique is based on super-resolved fluorescence and uses fluorophores to visualize objects at the atomic level by means of optical microscopes. There are two main methods used in super-resolution microscopy, namely, stimulated emission depletion (STED) and single fluorophore detection. Nanoscopy is primarily used in cell biology to observe the structural features of living organisms ranging from cells to proteins. It is also employed for investigations at the nanoscale and in real-time bio-interactions. Recently, an interest in the use of super-resolution microscopy in nanomedicine and bionanotechnology has arisen, paving the road for unprecedented advancements in diagnostic medical imaging.

This Special Issue aims to gather recent breakthroughs in super-resolution microscopy and its applications to nano-sciences. It also focuses on showcasing recent tools and protocol developments in nanoscopy and its applications within and beyond the life sciences.    

Dr. Elisabetta Canetta
Guest Editor

Manuscript Submission Information

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Keywords

  • Nanoscopy
  • Stimulated emission depletion
  • Single fluorophore detection
  • Diagnostic medical imaging
  • Nanomedicine
  • Real-time bio-interactions at the nanoscale
  • Bionanotechnology

Published Papers (2 papers)

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Research

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9 pages, 2542 KiB  
Communication
Observations of Nematicity, Dopants, and Zero-Bias Conductance Peaks for the Ca0.9La0.1FeAs2 Superconductor
by Jae-Joon Kim, Min Seok Park, Kyoung Seok Lee, Sang Hyun Joo, Jung Hoon Yoo, Dilip Bhoi, Byeong Hun Min, Kee Hoon Kim and Jinho Lee
Nanomaterials 2023, 13(4), 622; https://0-doi-org.brum.beds.ac.uk/10.3390/nano13040622 - 04 Feb 2023
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Abstract
Ca1−xLaxFeAs2 (CLFA112) belongs to a new family of Fe-based superconductors (FeSCs) and has a unique crystal structure featuring an arsenic zigzag chain layer, which has been proposed to be a possible two-dimensional topological insulator. This suggests that CLFA112 [...] Read more.
Ca1−xLaxFeAs2 (CLFA112) belongs to a new family of Fe-based superconductors (FeSCs) and has a unique crystal structure featuring an arsenic zigzag chain layer, which has been proposed to be a possible two-dimensional topological insulator. This suggests that CLFA112 is a potential topological superconductor—a platform to realize Majorana fermions. Up to now, even a clear superconducting (SC) gap in CLFA112 has never been observed, and the SC properties of CLFA112 remain largely elusive. In this letter, we report the results of an atomic-scale investigation of the electronic structure of CLFA112 crystals using low-temperature scanning tunneling microscopy (STM). We revealed four different types of surfaces exhibiting distinct electronic properties, with all surfaces displaying dominating 2 × 1 surface reconstructions. On a Ca/La layer on top of an FeAs layer, a clear SC gap of ~12 mV was observed only at the crevices (vacancies) where the FeAs layer can be directly accessed. Remarkably, the FeAs termination layer displayed a dispersing nematic modulation both in real and q space. We also present peculiar zero-bias conductance peaks for the very As chain layer that is believed to exhibit a topological edge state as well as the influence of La dopants on the As chain layer. Full article
(This article belongs to the Special Issue Super-resolution Microscopy and Nanoscience)
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Review

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16 pages, 3682 KiB  
Review
When Super-Resolution Localization Microscopy Meets Carbon Nanotubes
by Somen Nandi, Karen Caicedo and Laurent Cognet
Nanomaterials 2022, 12(9), 1433; https://0-doi-org.brum.beds.ac.uk/10.3390/nano12091433 - 22 Apr 2022
Cited by 7 | Viewed by 2553
Abstract
We recently assisted in a revolution in the realm of fluorescence microscopy triggered by the advent of super-resolution techniques that surpass the classic diffraction limit barrier. By providing optical images with nanometer resolution in the far field, super-resolution microscopy (SRM) is currently accelerating [...] Read more.
We recently assisted in a revolution in the realm of fluorescence microscopy triggered by the advent of super-resolution techniques that surpass the classic diffraction limit barrier. By providing optical images with nanometer resolution in the far field, super-resolution microscopy (SRM) is currently accelerating our understanding of the molecular organization of bio-specimens, bridging the gap between cellular observations and molecular structural knowledge, which was previously only accessible using electron microscopy. SRM mainly finds its roots in progress made in the control and manipulation of the optical properties of (single) fluorescent molecules. The flourishing development of novel fluorescent nanostructures has recently opened the possibility of associating super-resolution imaging strategies with nanomaterials’ design and applications. In this review article, we discuss some of the recent developments in the field of super-resolution imaging explicitly based on the use of nanomaterials. As an archetypal class of fluorescent nanomaterial, we mainly focus on single-walled carbon nanotubes (SWCNTs), which are photoluminescent emitters at near-infrared (NIR) wavelengths bearing great interest for biological imaging and for information optical transmission. Whether for fundamental applications in nanomaterial science or in biology, we show how super-resolution techniques can be applied to create nanoscale images “in”, “of” and “with” SWCNTs. Full article
(This article belongs to the Special Issue Super-resolution Microscopy and Nanoscience)
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