Retroviruses: Molecular Biology, Immunology and Pathogenesis
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 1638
Special Issue Editor
Interests: retrovirology; structural virology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Infections by retroviruses constitute a major health issue in humans, with Human Immunodeficiency Virus (HIV) being the etiological agent of AIDS, and Human T-Cell Leukemia Virus type 1 causing adult T-cell leukemia or a neurodegenerative disease named HTLV-1-associated myelopathy/tropical spastic paraparesis.
Retroviral infections are also a major veterinary problem as they induce various pathologies in a wide range of domestic and wild animals, from poultry, cats, cattle and horses to lions, monkeys and koalas.
It is interesting to note that some exogenous infections can lead to the permanent insertion of retroviral elements in the genome of the infected species. These endogenous retroviruses (ERVs) are estimated to represent 1 to 5 percent of the human genome. They have influenced the evolution of some species, and their activation can also be linked to several diseases.
This wide variety of retroviral species and their associated pathogenicity involves specific replication strategies, regulatory mechanisms, virus–host interactions and/or escape from host restriction factors or from the host’s immune system. New understandings of these different aspects have recently been obtained with the development of new imaging and analysis techniques.
This Special Issue of Pathogens aims to bring together articles or reviews dealing with the most recent developments of all aspects of the research on human and animal retroviruses, from molecular and structural biology or recent -omics analysis, to virus–cell interactions, immunology and disease development, control or therapy in infected individuals. This will provide a comprehensive and up-to-date overview of the mechanisms underlying retroviral infections, replication, activation, host–virus interactions, and pathogenicity.
We look forward to receiving your contributions.
Dr. Christophe Guillon
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- retroviruses
- retroviral infections
- viral replication
- host-virus interactions
- molecular and structural biology
- virus-cell interactions
- immunology
- therapy
