Molecular Epidemiology, Genetics and Infection Biology of the Genus Campylobacter

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".

Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 1902

Special Issue Editors


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Guest Editor
Division of Biomedical Food Research, National Institute of Health Sciences, Kawasaki, Kanagawa 210-9501, Japan
Interests: Campylobacter; food microbiology; infection biology; microbial ecology; bacterial stress response

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Guest Editor
Department of Bacteriology I, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan
Interests: Campylobacter; molecular genetics; gene regulation; gene transfer; genome instability

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Guest Editor
Faculty of Marine Bioscience, Fukui Prefectural University, Obama, Fukui, Japan
Interests: Campylobacter; host cell signaling; infection disease; virulence factor

Special Issue Information

Dear Colleagues,

Genus Campylobacter, in particular, C. jejuni and C. coli, are well-recognized as one of the leading causes of gastrointestinal illness worldwide, with possible consequences such as the development of Guillain–Barré syndrome (GBS), which is a rare disorder where a person’s own immune system damages their nerve cells, causing muscle weakness and, sometimes, paralysis. According to the European Food Safety Authority, approximately 220 thousands human campylobacteriosis were confirmed in 2019, in the EU and its occurrence rates was estimated to be 59.7 per 100,000 population (https://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/pmc/articles/PMC7913300/). To date, epidemiological surveillance has mounted evidence that these pathogens could be mainly transmitted via poultry and ruminants, throughout the food chain, to humans, whereas a part of human campylobacteriosis has originated from other sources, such as wild birds and hostile environments. The latter issue thus suggested the possible transmission vehicle of wild animals or environments of the pathogenic microorganism. Thus, the source attribution study, as well as monitoring and improvement of hygienic control at slaughter and processing facilities of the associated foods, have social impacts for developing feasible strategies to reduce human infection.

Among the genus Campylobacter, other species, such as C. lari, C. hyointestinalis, C. fetus are also linked to a series of human infection. The impact of these infectious agents on health ramified into a broader social need to address not only the biology, but also the social, economic, and psychological costs of the associated diseases on our lives. For this Special Issue, we sincerely invite you to send the original articles or review articles on aspects of the biology relating to the genus Campylobacter, from multiple viewpoints such as food safety, microbiology, infection biology, and molecular epidemiology.

Dr. Hiroshi Asakura
Dr. Shouji Yamamoto
Dr. Takaaki Shimohata
Guest Editors

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Keywords

  • Campylobacter
  • molecular epidemiology
  • source attribution
  • pathogenesis
  • environmental survival mechanism
  • cellular metabolism
  • comparative genomics (and proteomics)
  • host-pathogen interaction
  • intrahost dynamics

Published Papers (1 paper)

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Research

9 pages, 451 KiB  
Article
First Data on Campylobacter spp. Presence in Shellfish in Croatia
by Luka Jurinović, Biljana Ječmenica, Natalija Džafić, Diana Brlek Gorski, Borka Šimpraga, Fani Krstulović, Tajana Amšel Zelenika and Andrea Humski
Pathogens 2022, 11(8), 943; https://0-doi-org.brum.beds.ac.uk/10.3390/pathogens11080943 - 19 Aug 2022
Cited by 2 | Viewed by 1469
Abstract
This study aimed to assess the presence of thermotolerant Campylobacter spp., as one of the most important foodborne zoonotic pathogens, in three shellfish species: mussels (Mytilus galloprovincialis), oysters (Ostrea edulis) and queen scallops (Aequipecten opercularis). The samples [...] Read more.
This study aimed to assess the presence of thermotolerant Campylobacter spp., as one of the most important foodborne zoonotic pathogens, in three shellfish species: mussels (Mytilus galloprovincialis), oysters (Ostrea edulis) and queen scallops (Aequipecten opercularis). The samples were collected from nine locations in the Istrian aquatory, Croatia. Isolation of Campylobacter was done according to standard ISO method, and species were identified using multiplex PCR. Isolates identified as C. jejuni and C. lari were genotyped using multilocus sequence typing (MLST) to determine the potential source of contamination. Among 108 examined samples of bivalve molluscs, mussels dominated and were the only ones found positive for the presence of Campylobacter (25.6%). In total, 19 C. lari and 1 C. jejuni strains were isolated. C. lari isolates found in this study belong to 13 sequence types (STs), and 9 of them are newly described in this paper. Two out of the four previously described C. lari STs that were found in this study were previously found in human stool. The only C. jejuni isolate was found to be sequence type 1268, which belongs to ST-1275 clonal complex that is almost exclusively found in seabirds and can sporadically cause infection in humans. Regarding the obtained results, introducing surveillance of thermotolerant Campylobacter in shellfish in the Republic of Croatia is advised as an improvement for public health safety. Full article
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