Bioactivity of Fruits Extracts

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: closed (20 June 2023) | Viewed by 3364

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Department of Biochemistry and Applied Biosciences, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan
Interests: plant breeding; genetics; citrus; blueberry; raspberry; polyploid; chromosome
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Special Issue Information

Dear Colleagues,

Fruit species are largely appreciated and highly consumed throughout the world. There are several biological reasons why the consumption of fruits might reduce or prevent chronic diseases. Fruits are rich sources of nutrients and energy and contain vitamins, minerals, fiber and numerous other classes of biologically active compounds. Moreover, parts of fruit crops such as fruit peels, leaves and barks also possess medicinal properties and have been included in this review. This Special Issue of Plants will thus highlight the bioactive and chemical profiles of health-related compounds of various fruit tree tissues and organs for medical and pharmaceutical applications. This Special Issue also focuses on recent advances in physiological and molecular biological studies conducted to elucidate the absorption and metabolism of health-related compounds.

Prof. Dr. Hisato Kunitake
Guest Editor

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Published Papers (2 papers)

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Research

14 pages, 1008 KiB  
Article
Phytochemical Analysis and Biological Activities of Ripe Fruits of Mistletoe (Psittacanthus calyculatus)
by Zaida Ochoa-Cruz, Jorge Molina-Torres, María V. Angoa-Pérez, Jeanette G. Cárdenas-Valdovinos, Ignacio García-Ruiz, José A. Ceja-Díaz, José O. Bernal-Gallardo and Hortencia G. Mena-Violante
Plants 2023, 12(12), 2292; https://0-doi-org.brum.beds.ac.uk/10.3390/plants12122292 - 12 Jun 2023
Cited by 1 | Viewed by 1075
Abstract
Psittacanthus calyculatus is a hemiparasitic plant of an arboreal species (e.g., forest, fruit trees). Its foliage has therapeutic potential; however, little is known about its fruits. In this study, the phytochemical profile and biological activities of P. calyculatus fruits hosted by Prosopis laevigata [...] Read more.
Psittacanthus calyculatus is a hemiparasitic plant of an arboreal species (e.g., forest, fruit trees). Its foliage has therapeutic potential; however, little is known about its fruits. In this study, the phytochemical profile and biological activities of P. calyculatus fruits hosted by Prosopis laevigata and Quercus deserticola were evaluated. The fruits of P. calyculatus from P. laevigata showed the highest content of total phenols (71.396 ± 0.676 mg GAE/g DW). The highest content of flavonoids and anthocyanins was presented in those from Q. deserticola (14.232 ± 0.772 mg QE/g DW; 2.431 ± 0.020 mg C3GE/g DW). The anthocyanin cyanidin-3-glucoside was detected and quantified via high-performance thin-layer chromatography (HPTLC) (306.682 ± 11.804 mg C3GE/g DW). Acidified extracts from host P. laevigata showed the highest antioxidant activity via ABTS•+ (2,2′azinobis-(3-ethylbenzothiazdin-6-sulfonic acid) (214.810 ± 0.0802 mg TE/g DW). Fruit extracts with absolute ethanol from the P. laevigata host showed the highest antihypertensive activity (92 ± 3.054% inhibition of an angiotensin converting enzyme (ACE)). Fruit extracts from both hosts showed a minimum inhibitory concentration (MIC) of 6.25 mg/mL and a minimum bactericidal concentration (MBC) of 12.5 mg/mL against Escherichia coli, Salmonella choleraesuis and Shigella flexneri. Interestingly, a significant host effect was found. P. calyculatus fruits extract could be used therapeutically. However, further confirmation experiments should be carried out. Full article
(This article belongs to the Special Issue Bioactivity of Fruits Extracts)
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14 pages, 2432 KiB  
Article
Comparison of Proanthocyanidin Content in Rabbiteye Blueberry (Vaccinium virgatum Aiton) Leaves and the Promotion of Apoptosis against HL-60 Promyelocytic Leukemia Cells Using ‘Kunisato 35 Gou’ Leaf Extract
by Yuki Toyama, Yoko Fujita, Saki Toshima, Tomonari Hirano, Masao Yamasaki and Hisato Kunitake
Plants 2023, 12(4), 948; https://0-doi-org.brum.beds.ac.uk/10.3390/plants12040948 - 19 Feb 2023
Cited by 1 | Viewed by 1922
Abstract
Polyphenol-rich rabbiteye blueberry (Vaccinium virgatum Aiton) leaves have attracted attention as a food material. In this study, we compared the total polyphenols, total proanthocyanidin content, and antioxidant activity of the leaves of 18 blueberry varieties and investigated the seasonal variation in polyphenols. [...] Read more.
Polyphenol-rich rabbiteye blueberry (Vaccinium virgatum Aiton) leaves have attracted attention as a food material. In this study, we compared the total polyphenols, total proanthocyanidin content, and antioxidant activity of the leaves of 18 blueberry varieties and investigated the seasonal variation in polyphenols. We also evaluated the anti-cancer cell proliferation properties of the rabbiteye blueberry leaf specific cultivar ‘Kunisato 35 Gou’. Rabbiteye blueberry leaves had significantly higher total polyphenol and total proanthocyanidin values than northern highbush blueberry and southern highbush blueberry leaves. The antioxidant activity of blueberry leaves was highly positively correlated with both the total polyphenol and total proanthocyanidin content. Variations were observed in the total polyphenol and total proanthocyanidin content of rabbiteye blueberry leaves harvested at different points in the growing season; leaves collected in fall to winter contained more epicatechin in addition to proanthocyanidins. In the evaluation of anti-cancer cell proliferation properties against HL-60 promyelocytic leukemia cells, the September-harvested extracts of rabbiteye blueberry ‘Kunisato 35 Gou’ showed strong properties, and the use of an FITC Annexin V apoptosis detection kit with propidium iodide confirmed that this HL-60 cell death occurred via apoptosis. Limiting the harvest time would make rabbiteye blueberry leaves a more functional food ingredient. Full article
(This article belongs to the Special Issue Bioactivity of Fruits Extracts)
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