The Frontier and Progress of Bioprocess Technology

Dear Colleagues,

The Special Issue “The Frontier and Progress of Bioprocess Technology” will address the latest research in environmentally friendly bioprocess technology. Bioprocess technologies include bioenergy from lignocellulose materials, biomass gasification, biofuel/bioproduct production from agro-food waste, enzymatic bioprocess technology, food fermentation, bioprocesses optimization scale-up, and modeling.

Bioprocess technology is a vital part of biotechnology that deals with processes combining all living matter or its components with nutrients to produce specialty chemicals, reagents, and biotherapeutics. These processes form the backbone of translating discoveries of life sciences into useful industrial products. Different stages associated with bioprocess technology include substrates and medium preparation, biocatalyst selection and optimization, volume production, downstream processing, purification, and final processing.

A bioprocess can commonly be divided into three stages:

• Stage I: Upstream processing, which involves the preparation of liquid medium, separation of particulate and inhibitory chemicals from the medium, sterilization, air purification, etc. Upstream processes include the selection of a microbial strain characterized by the ability to synthesize a specific product with the desired commercial value. This strain is then subjected to improvement protocols to maximize its ability to synthesize economical amounts of the product.
• Stage II: Fermentation/anaerobic digestion, which involves the conversion of substrates to desired product with the help of biological agents such as microorganisms. Techniques for the large-scale production of microbial products must provide both an optimum environment for the microbial synthesis of the desired product and be economically feasible on a large scale.
• Stage III: Downstream processing, which involves the separation of cells from fermentation broth, the purification and concentration of a desired product, and waste disposal or recycling.

Therefore, the objective of this Special Issue is to showcase the diversity and advances in research contributing to developing effective bioprocess technologies.

Original papers on bioprocess technologies are solicited. We are particularly interested in receiving manuscripts that integrate biology and engineering research and/or experimental and theoretical studies. We invite researchers from all areas of bioengineering to submit manuscripts for this important Special Issue of Processes.

Dr. Birthe Nielsen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• upstream processing
• fermentation
• anaerobic digestion
• downstream processing
• bioprocessing
• biomass
• bioreactors