Theory and Modelling of Nanomechanical Systems Application in the Biomedical Field

Dear Colleagues,

Nanomechanical systems have been deeply studied for years due to its high potential as ultrasensitive mass sensors. They are mechanical structures with at least one of its dimensions in the nanoscale and the ability to change some measurable property as a result of the interaction with an external agent. During decades these systems have been proposed with many different shapes that can go from very basic forms like cantilever beams, nanowires or graphene sheets to more complex structures like arrays or multilayered systems. Depending on the application, the properties that are measured in order to obtain the information from the external agent can also be very different like deformation or resonance frequency for instance. Among the multiple applications of nanomechanical systems, biomedicine has brought the attention of researchers because today, it is more and more evident that mechanical properties of biological systems are intimately related to the development of diseases. For instance, it is known that some viruses change their stiffness during the maturation process or that metastatic cells are softer than healthy cells allowing them to migrate easier to other parts of the body. Nanomechanical systems are excellent transducers of the mechanical properties of biological systems and the research and study of these devices is already playing a key role in the biomedical field. However, the translation between what it is measured and the biological information is not an easy task and requires the use of theoretical models involving different fields like physics, chemistry, biology or engineering. This Special Issue aims to inventory the latest achievements in theory and modelling of nanomechanical systems and welcomes papers concerning innovation and development in theory, methods and modelling of new devices with application in the biomedical field.

Dr. Jose Jaime Ruz Martinez
Dr. Oscar Malvar Vidal
Guest Editors

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• Nanotechnology
• Biomedicine
• Biosensors
• Mechanics
• Theory
• Modelling