Dear Colleagues,                

The identification of high-value bio-products from natural sources is a fact of wide dissemination in light of the advances in the development of increasingly efficient and sensitive analytical techniques. However, the methods developed so far to obtain these compounds from their natural sources have limitations when scaled at a larger size and the implied time- and solvent-consuming nature of the operations. Therefore, to contribute to the potential commercial use of extractable bio-products from microalga, cyanobacteria, higher plants and fruits, greater efforts are required in the fields of research and the development of isolation systems, using an efficient, cost-effective, and scalable isolation technology. In this context, countercurrent chromatography (CCC) and centrifugal partition chromatography (CPC), two liquid–liquid chromatography techniques, have emerged as valuable alternatives due to their high efficiency and proved scalability. This Special Issue refers to the applications of CCC and CPC for obtaining valuable compounds from natural sources at the laboratory and larger scales.

Dr. José Cheel
Guest Editor

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• Countercurrent chromatography
• Centrifugal partition chromatography
• High-value products
• Liquid–liquid separation
• Separation technology
• Natural products
• Scaling-up