Symmetry versus Asymmetry in Cell Biology

A special issue of Symmetry (ISSN 2073-8994). This special issue belongs to the section "Life Sciences".

Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 3780

Special Issue Editors


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Guest Editor
1. Division of Cellular and Molecular Biology & Histology, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania
2. "Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania
Interests: prognostic markers; cancer biomarkers; cancer biology; cancer metastasis; metastasis
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Victor Babes National Institute of Pathology, 050096 Bucharest, Romania
2. Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania
Interests: skeletal muscle; myogenesis; regeneration; cell culture; regenerative medicine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Far from obvious sometimes, symmetry can be easily disclosed in almost every domain of cell biology. Usually properly associated with cell morphology or architecture (structure and ultrastructure), symmetry and asymmetry  can be also viewed, metaphorically, as a yin and yang that the equilibrium of cell function(s) is relying on.

We are soliciting contributions (research and review articles) covering a broad range of topics on symmetry versus asymmetry in cell biology, including (though not limited to) the following:

  • Molecular mechanisms of cell polarization
  • Symmetric versus asymmetric cell division
  • Mechanisms of asymmetry during development
  • Symmetry breaking cell signals
  • Dorsiventrality, patterns and branching systems
  • Symmetry versus asymmetry in molecular cell interactions
  • Cell space fillers: staking and packing
  • Symmetry breaking during movements
  • Maintaining internal (a)symmetries (spatial or temporal regulators of localization or interaction)
  • Exploiting symmetry in antiviral strategies
  • Apoptosis and a(symmetry)
  • Organelle shape and cell activity

Dr. Mihail E. Hinescu
Dr. Laura Cristina Ceafalan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Symmetry is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Cell polarization
  • Asymmetric cell division
  • Symmetry breaking in development
  • Dorsiventrality
  • Patterns and branching systems
  • Symmetry in molecular cell interactions
  • Staking and packing
  • Internal (a)symmetries
  • Exploiting symmetry in antiviral strategies
  • Apoptosis and a(symmetry)
  • Organelle shape

Published Papers (1 paper)

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Review

7 pages, 3007 KiB  
Review
Analysis of Asymmetric Cell Division Using Human Neuroblastoma Cell Lines as a Model System
by Hideki Izumi, Yasuhiko Kaneko and Akira Nakagawara
Symmetry 2021, 13(10), 1907; https://0-doi-org.brum.beds.ac.uk/10.3390/sym13101907 - 11 Oct 2021
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Abstract
Neuroblastoma is one of the most common childhood solid tumors and develops from neural stem cells that normally comprise the embryonic structure termed the neural crest. Human neuroblastoma cell lines have special properties as they exhibit cell growth and are induced to become [...] Read more.
Neuroblastoma is one of the most common childhood solid tumors and develops from neural stem cells that normally comprise the embryonic structure termed the neural crest. Human neuroblastoma cell lines have special properties as they exhibit cell growth and are induced to become mature neurons by drugs such as retinoid. Therefore, we examined asymmetric cell division (ACD) using human neuroblastoma cells as an ACD model, and confirmed that ACD in human cancer cells is evolutionally conserved. Furthermore, we demonstrated that MYCN is involved in cell division fate. We introduce the brief history of ACD study using neuroblastoma cell lines and discuss why human neuroblastoma cells are an ideal model system for clarifying the mechanism of ACD. Full article
(This article belongs to the Special Issue Symmetry versus Asymmetry in Cell Biology)
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