Vaccine Uptake in Italy, through the OBVIOUS Project and Other Independent Research

A special issue of Vaccines (ISSN 2076-393X).

Deadline for manuscript submissions: 31 December 2024 | Viewed by 4188

Special Issue Editors

Special Issue Information

Dear Colleagues,

We welcome you to contribute to our Special Issue dedicated to vaccine uptake in Italy. This research area is of significant importance in the context of public health, especially in light of global challenges such as the COVID-19 pandemic. 

Understanding and enhancing vaccine uptake is vital for achieving herd immunity, preventing disease outbreaks, and safeguarding the health of communities. With these goals in mind, the OBVIOUS Project (Observatory on Vaccine Hesitancy in Italy—Online UniBo Surveys) was launched in 2022 and will continue its activity in 2023, providing significant insights into vaccine uptake in Italy. 

This Special Issue aims to explore the factors influencing vaccine uptake in Italy and to offer strategies to enhance vaccination rates. Our goal is to compile a comprehensive collection of rigorous, peer-reviewed evidence regarding vaccination rates and strategies to improve them. 

We welcome both original research articles and reviews that explore various aspects of vaccine uptake in Italy. Potential research areas include articles examining vaccine rates, vaccine uptake, and vaccine hesitancy. 

We look forward to receiving your contributions.

Dr. Davide Gori
Dr. Jacopo Lenzi
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vaccine uptake
  • vaccine hesitancy
  • vaccination rates
  • Italy

Published Papers (4 papers)

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Research

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10 pages, 848 KiB  
Article
The Role of Pharmacists in Counteracting Vaccine Hesitancy: Effectiveness of the 2019 Carnia Project in Improving Adherence to Influenza Vaccination among Target Population
by Gloria Longobardi, Laura Brunelli, Benedetta Piciocchi, Andrea Morsanutto, Andrea Iob, Flavio Schiava, Claudio Luigi Pancino, Luca Degrassi, Giuseppe Tonutti, Silvio Brusaferro and Luca Arnoldo
Vaccines 2024, 12(3), 331; https://0-doi-org.brum.beds.ac.uk/10.3390/vaccines12030331 - 20 Mar 2024
Viewed by 862
Abstract
Vaccine hesitancy has been included among the top ten threats to global health by the World Health Organization. Pharmacists can play a pivotal role in removing the individual barrier to vaccination, because of the relationship of trust they have with citizens and their [...] Read more.
Vaccine hesitancy has been included among the top ten threats to global health by the World Health Organization. Pharmacists can play a pivotal role in removing the individual barrier to vaccination, because of the relationship of trust they have with citizens and their ease of access. The aim of this study was to examine the impact of a pharmacy-based intervention to support the 2019 influenza vaccination campaign conducted in the Carnia district through one-to-one counseling. We analyzed data collected by pharmacists between 22 October 2019 and 20 January 2020, and trends in vaccination adherence in the context of the Local Health Authority and the entire province of Udine since 2016. The results showed that 77.2% of people who had not received an influenza vaccination in the previous year changed their minds about vaccination after receiving counseling. The pharmacy-based intervention improved influenza vaccination adherence in the target district (+13.4%), even when compared to the neighboring district of Gemona or considering the data in the broader local and provincial context, and this effect was particularly pronounced among those aged 65 to 74 years (p < 0.01). Considering these findings, pharmacies should be more effectively involved in the provision of public health services aimed at improving accessibility, timeliness, and equity. Full article
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19 pages, 2359 KiB  
Article
Human Papillomavirus (HPV) Vaccine Coverage and Confidence in Italy: A Nationwide Cross-Sectional Study, the OBVIOUS Project
by Marco Montalti, Aurelia Salussolia, Angelo Capodici, Francesca Scognamiglio, Zeno Di Valerio, Giusy La Fauci, Giorgia Soldà, Maria Pia Fantini, Anna Odone, Claudio Costantino, Julie Leask, Heidi J. Larson, Jacopo Lenzi and Davide Gori
Vaccines 2024, 12(2), 187; https://0-doi-org.brum.beds.ac.uk/10.3390/vaccines12020187 - 12 Feb 2024
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Abstract
Background: Human Papillomavirus (HPV) vaccination rates are still below the target due to vaccine refusal or delay, lack of knowledge, and logistical challenges. Understanding these barriers is crucial for developing strategies to improve HPV vaccination rates. Methods: This cross-sectional study used a questionnaire [...] Read more.
Background: Human Papillomavirus (HPV) vaccination rates are still below the target due to vaccine refusal or delay, lack of knowledge, and logistical challenges. Understanding these barriers is crucial for developing strategies to improve HPV vaccination rates. Methods: This cross-sectional study used a questionnaire to investigate social and behavioral factors influencing decision making about the HPV vaccine. The survey was conducted from 11 April to 29 May 2022 and involved 10,000 Italian citizens aged ≥ 18 years. The sample was stratified based on region of residence, gender, and age group. Results: 3160 participants were surveyed about themselves, while 1266 respondents were surveyed about their children’s vaccine uptake. Among females aged ≥ 26 years, the national average HPV vaccine uptake was 21.7%, with variations across different regions. In the 18–25 age group, females had a vaccine uptake (80.8%) twice as much as males (38.1%), while vaccine uptake among male and female children aged 9–11 was similar. Conclusions: The OBVIOUS study in Italy reveals factors influencing low HPV vaccine uptake, suggesting targeted approaches, tailored information campaigns, heightened awareness of eligibility, promoting early vaccination, addressing low-risk perception among males, addressing safety concerns, and enhancing perceived accessibility to improve vaccine uptake and mitigate health risks. Full article
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16 pages, 1139 KiB  
Article
Vaccine Hesitancy and Public Mistrust during Pandemic Decline: Findings from 2021 and 2023 Cross-Sectional Surveys in Northern Italy
by Verena Barbieri, Christian J. Wiedermann, Stefano Lombardo, Giuliano Piccoliori, Timon Gärtner and Adolf Engl
Vaccines 2024, 12(2), 176; https://0-doi-org.brum.beds.ac.uk/10.3390/vaccines12020176 - 08 Feb 2024
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Abstract
This study examines vaccine agreements in South Tyrol, Italy, within distinct socio-cultural and linguistic contexts. Using data from the 2021 and 2023 “COVID-19 Snapshot Monitoring” extended surveys, we assessed changes in attitudes towards COVID-19 and other vaccinations during the second and final years [...] Read more.
This study examines vaccine agreements in South Tyrol, Italy, within distinct socio-cultural and linguistic contexts. Using data from the 2021 and 2023 “COVID-19 Snapshot Monitoring” extended surveys, we assessed changes in attitudes towards COVID-19 and other vaccinations during the second and final years of the pandemic. Multivariate logistic regression analysis was used to examine factors such as trust in institutions, language groups, and the use of complementary and alternative medicine. The representativeness of the study is supported by good participation rates, ensuring a comprehensive view of attitudes towards vaccination in the region. The results show a shift in public agreement with the national vaccination plan to 64% by 2023, from a rate of about 73% agreement in 2021 (p < 0.001). A significant decrease in trust in health authorities and a negative correlation with complementary and alternative medicine consultations were observed. The results highlight the complex nature of vaccine hesitancy in diverse regions such as South Tyrol and underline the need for targeted communication strategies and trust-building initiatives to effectively reduce hesitancy. This study provides critical insights for the formulation of public health strategies in diverse sociocultural settings. Full article
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Review

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13 pages, 277 KiB  
Review
Improving Influenza Vaccination Coverage in Patients with Cancer: A Position Paper from a Multidisciplinary Expert Group
by Paolo Bonanni, Michele Maio, Giordano D. Beretta, Giancarlo Icardi, Alessandro Rossi and Saverio Cinieri
Vaccines 2024, 12(4), 420; https://0-doi-org.brum.beds.ac.uk/10.3390/vaccines12040420 - 16 Apr 2024
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Abstract
Patients with cancer can be immunocompromised because of their disease and/or due to anticancer therapy. In this population, severe influenza virus infections are associated with an elevated risk of morbidity and mortality. Influenza vaccination is therefore highly recommended in cancer patients, including those [...] Read more.
Patients with cancer can be immunocompromised because of their disease and/or due to anticancer therapy. In this population, severe influenza virus infections are associated with an elevated risk of morbidity and mortality. Influenza vaccination is therefore highly recommended in cancer patients, including those receiving anticancer therapy. However, vaccination coverage remains far below the recommended target for vulnerable subjects. Six specialists in oncology, hematology, immunology, and public health/vaccinology convened with the objective of developing strategies, based on evidence and clinical experience, for improving influenza vaccination coverage in cancer patients. This viewpoint provides an overview of current influenza vaccination recommendations in cancer patients, discusses barriers to vaccination coverage, and presents strategies for overcoming said barriers. New immunization issues raised by the COVID-19 pandemic are also addressed. Future directions include improving public education on influenza vaccination, providing the media with accurate information, improving knowledge among healthcare professionals, improving access to vaccines for cancer patients, co-administration of the influenza and COVID-19 vaccines, increased collaboration between oncologists and other health professionals, increased accessibility of digital vaccination registries to specialists, shared information platforms, and promoting immunization campaigns by healthcare systems with the support of scientific societies. Full article
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