Management of COVID-19 through Vaccination: Past, Current and Future Strategies

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "COVID-19 Vaccines and Vaccination".

Deadline for manuscript submissions: closed (28 February 2024) | Viewed by 3916

Special Issue Editor


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Guest Editor
Barwon South West Public Health Unit, Barwon Health, Geelong, VIC, Australia
Interests: public health; epidemiology; policy; health systems

Special Issue Information

Dear Colleagues,

The last three years of the COVID-19 pandemic have recorded some of the best public health interventions, including the development of surveillance systems and tools, and widespread non-pharmaceutical interventions such as lock-downs and stay-at-home restrictions. Furthermore, pharmaceutical control, including vaccination, testing and antiviral treatment, has highly contributed to the reduction in the severity of the disease, and in turn reduced the burden on healthcare systems, globally. In many places, these control strategies were used alongside public involvement, sound policy and active communication, as described by Stenseth and colleagues. Nevertheless, unfavorable health impacts, including hospitalization and deaths, were reported. In Australia, an estimated 3.5% excess deaths were recorded in 2021 compared to −1.2% in 2020 and 0.9% in 2019. Additionally, the pandemic also highlighted key social determinants of health affecting the rollout of vaccination and other control strategies in certain populations and regions. 

This Special Issue will aim to disseminate empirical evidence of the success and challenges faced in the implementation of vaccination and other control strategies used to manage COVID-19 cases and outbreaks within various populations. Articles reflecting on the contribution, utilization, regulation, epidemiology and the safety of COVID-19 vaccination and other public health control strategies will be given a higher priority. Articles providing insights into the future of COVID-19 vaccination, as well as those describing the lessons learned to control future epidemics, will be highly considered.

I am pleased to invite you and any members of your research team to submit manuscripts for this Special Issue of the Vaccines journal. The Vaccines journal is an international, peer-reviewed open access journal focused on laboratory and clinical vaccine research, utilization and immunization. Original research articles, reviews and opinion pieces are welcome. 

I look forward to receiving your contributions.

Dr. Michael Muleme
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vaccination
  • COVID-19 transmission
  • regulation
  • vaccine safety
  • epidemiology
  • vaccine utilisation
  • control strategies

Published Papers (3 papers)

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Research

12 pages, 924 KiB  
Article
SARS-CoV-2 Symptoms during the Omicron Surge Differ between Boosted and Vaccinated Non-Boosted Persons
by Marisa A. Montecalvo, Paul Visintainer, Elizabeth Drugge, Katherine Kowalski, Rosemarie Raffa, Donna McKenna, Christine Moronta and Gary P. Wormser
Vaccines 2024, 12(3), 327; https://0-doi-org.brum.beds.ac.uk/10.3390/vaccines12030327 - 19 Mar 2024
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Abstract
Purpose: To determine the impact of booster COVID-19 vaccination on SARS-CoV-2 symptoms. Background: The Omicron surge of infections provided an opportunity to evaluate symptoms in relation to booster receipt. Methods: At a US medical college, the number, type, and duration of symptoms [...] Read more.
Purpose: To determine the impact of booster COVID-19 vaccination on SARS-CoV-2 symptoms. Background: The Omicron surge of infections provided an opportunity to evaluate symptoms in relation to booster receipt. Methods: At a US medical college, the number, type, and duration of symptoms were evaluated for 476 students or employees, factoring in days between last vaccination and SARS-CoV-2 diagnosis. Results: Compared with vaccinated non-boosted individuals, boosted individuals reported a significantly higher frequency of nasal congestion (57.9% vs. 44.4%, p = 0.018) and nasal congestion and/or sore throat (77.2% vs. 62.0%, p = 0.003); in contrast, the frequency of body/muscle aches was significantly less among boosted individuals (22.1% vs. 32.4%, p = 0.038). With each one week increase in time since booster receipt, the probability of fever increased significantly by 4.4% (OR 1.044, 95% CI 1.01, 1.07, p = 0.001), and the probability of cough increased significantly by 4.8% (OR 1.048, 95% CI 1.01, 10.8, p= 0.010). Conclusions: Within a medical college population, during the first 7 months of the Omicron surge of infections, compared with vaccinated non-boosted individuals, boosted individuals significantly more often reported the following: nasal congestion as well as nasal congestion and/or sore throat. In contrast, body/muscle aches were reported significantly less often. The rates of fever and cough each significantly increased as time since booster dose receipt increased. These data suggest that having had a booster vaccination, as well the timing of receiving it, impacts the clinical manifestations of breakthrough SARS-CoV-2 infections. Additional studies are needed to precisely define SARS-CoV-2 symptoms in relation to booster vaccinations. Full article
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12 pages, 257 KiB  
Article
Psychosocial Factors Influencing Parents’ Acceptance of COVID-19 Vaccination for Their Children: An Italian Cross-Sectional Study
by Miriam Capasso, Marcella Bianchi and Daniela Caso
Vaccines 2024, 12(3), 317; https://0-doi-org.brum.beds.ac.uk/10.3390/vaccines12030317 - 17 Mar 2024
Viewed by 938
Abstract
Vaccine hesitancy poses a significant threat to the health of individuals across all age groups, which has been exacerbated by the COVID-19 pandemic. In this cross-sectional study, an extension of the Theory of Planned Behavior (TPB) was applied to investigate psychosocial variables predicting [...] Read more.
Vaccine hesitancy poses a significant threat to the health of individuals across all age groups, which has been exacerbated by the COVID-19 pandemic. In this cross-sectional study, an extension of the Theory of Planned Behavior (TPB) was applied to investigate psychosocial variables predicting intention to vaccinate children under 12 against COVID-19 in a sample of 420 Italian parents (Mean age = 40.4, SD = 5.9; Women = 78.1%). Hierarchical regression analysis revealed that, among the TPB variables, cognitive attitude, descriptive norms, and perceived behavioral control significantly predicted parents’ vaccination intention. Furthermore, including trust in the institutions’ ability to manage the vaccination campaign in the model significantly increased the explained variance in intention. These findings suggest that campaigns promoting childhood COVID-19 vaccination should not only emphasize the safety and effectiveness of vaccines for children but also focus on reducing barriers to vaccination. Additionally, attention should be given to enhancing the perception that this behavior is widespread among other parents, thus leveraging the power of social influence. Finally, and not less important, significant efforts should be directed toward building and reinforcing trust in the system of actors promoting and managing the COVID-19 vaccination campaign. Full article
14 pages, 1413 KiB  
Article
A Survey of Fear for Others, Fear for Self, and Pandemic Anxiety Predicting Intention to Take the First Booster Vaccine to Combat COVID-19
by Joseph N. Scudder and Dennis P. DeBeck
Vaccines 2024, 12(1), 47; https://0-doi-org.brum.beds.ac.uk/10.3390/vaccines12010047 - 31 Dec 2023
Viewed by 1102
Abstract
This study examined the impact of fear and anxiety on the intent to take the first COVID-19 booster vaccine. The objective of this study is to provide guidance for messaging campaigns of public health practitioners. A survey approach provided insights about individuals’ emotions [...] Read more.
This study examined the impact of fear and anxiety on the intent to take the first COVID-19 booster vaccine. The objective of this study is to provide guidance for messaging campaigns of public health practitioners. A survey approach provided insights about individuals’ emotions of fear and anxiety related to adopting the first booster vaccine for the Coronavirus disease 2019 (COVID-19). Methods: Three independent variables were considered in their ability to predict the intent to take the first COVID-19 booster vaccine (BINT): Fear for Others (FOTH), Fear for SELF (FSELF), and COVID-19 Anxiety (CANX). Results: The confirmatory factor analysis supported an underlying three-factor solution for three central emotions in this study. A path analysis indicated significant direct effects for FOTH and FSELF in the prediction of BINT. The interdependent nature of these variables on the intent to get the first booster vaccine also was indicated by significant indirect effects. Discussion: Fear should be more precisely refined to include the fear for others (FOTH) beyond consideration of the fear for self (FSELF) from the impact of COVID-19. Conclusions: FOTH and FSELF were demonstrated to be direct predictors of BINT. CANX was only found to be significant as part of indirect effects impacting BINT. Future investigation should be given to the mediating role of anxiety with FOTH and FSELF as the context changes. Full article
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