The Development of SARS-CoV-2 Vaccines Using Various Strategies

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "COVID-19 Vaccines and Vaccination".

Deadline for manuscript submissions: closed (20 April 2022) | Viewed by 2803

Special Issue Editor


E-Mail Website
Guest Editor
Department of Molecular Virology Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan
Interests: influenza viruses; Ebola virus; SARS-CoV-2; zoonotic viruses; pathogenicity; virus–host interaction; vaccines; adjuvants
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

SARS-CoV-2, which emerged at the end of 2019, is still rampant around the world, causing enormous health and economic damage. The development of SARS-CoV-2 vaccines has proceeded at an unprecedented pace, and several vaccines have already been approved and administered in many countries. However, despite expectations that global vaccination will lead to the end of the pandemic, variants possessing amino acid substitutions in the antigenic sites of the SARS-CoV-2 spike protein continue to emerge all over the world, raising concerns about the effectiveness of the current vaccines. Therefore, it is important to continue to develop vaccines using strategies that improve our preparedness for these emerging variants. In this Special Issue, we seek articles (both reviews and original research) discussing the development of SARS-CoV-2 vaccines using various strategies.

Dr. Tokiko Watanabe
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • SARS-CoV-2
  • vaccines
  • animal models
  • variants
  • vaccine platforms

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

9 pages, 349 KiB  
Article
COVID-19 Vaccination Is Safe among Mast Cell Disorder Patients, under Adequate Premedication
by Tiago Azenha Rama, Joana Miranda, Diana Silva, Luís Amaral, Eunice Castro, Alice Coimbra, André Moreira and José Luís Plácido
Vaccines 2022, 10(5), 718; https://0-doi-org.brum.beds.ac.uk/10.3390/vaccines10050718 - 04 May 2022
Cited by 9 | Viewed by 2345
Abstract
Reported cases of anaphylaxis following COVID-19 vaccination raised concerns about the safety of these vaccines, namely in patients suffering from clonal mast cell (MC) disorders—a heterogenous group of disorders in which patients may be prone to anaphylaxis caused by vaccination. This study aimed [...] Read more.
Reported cases of anaphylaxis following COVID-19 vaccination raised concerns about the safety of these vaccines, namely in patients suffering from clonal mast cell (MC) disorders—a heterogenous group of disorders in which patients may be prone to anaphylaxis caused by vaccination. This study aimed to assess the safety of COVID-19 vaccines in patients with clonal MC disorders. We performed an ambidirectional cohort study with 30 clonal MC disorder patients (n = 26 in the prospective arm and n = 4 in the retrospective arm), that were submitted to COVID-19 vaccination. Among these, 11 (37%) were males, and median age at vaccination date was 41 years (range: 5y to 76y). One patient had prior history of anaphylaxis following vaccination. Those in the prospective arm received a premedication protocol including H1- and H2-antihistamines and montelukast, while those in the retrospective arm did not premedicate. Overall, patients received a total of 81 doses, 73 under premedication and 8 without premedication. No MC activation symptoms were reported. COVID-19 vaccination seems to be safe in patients with clonal mast cell disorders, including those with prior anaphylaxis following vaccination. Robust premedication protocols may allow for vaccination in ambulatory settings. Full article
(This article belongs to the Special Issue The Development of SARS-CoV-2 Vaccines Using Various Strategies)
Show Figures

Figure 1

Back to TopTop