Correction: Paszkiewicz et al. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting That Central Effects Can Be Avoided. Int. J. Mol. Sci. 2020, 21, 6639

Paszkiewicz, Rebecca L.; Bergman, Richard N.; Santos, Roberta S.; Frank, Aaron P.; Woolcott, Orison O.; Iyer, Malini S.; Stefanovski, Darko; Clegg, Deborah J.; Kabir, Morvarid

doi:10.3390/ijms22094366

Open AccessCorrection

Correction: Paszkiewicz et al. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting That Central Effects Can Be Avoided. Int. J. Mol. Sci. 2020, 21, 6639

by

Rebecca L. Paszkiewicz

¹,

Richard N. Bergman

¹,

Roberta S. Santos

¹

,

Aaron P. Frank

¹,

Orison O. Woolcott

¹,

Malini S. Iyer

¹,

Darko Stefanovski

²,

Deborah J. Clegg

³ and

Morvarid Kabir

^1,*

¹

Sports Spectacular Diabetes and Obesity Wellness and Research Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA

²

School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA

³

The College of Nursing and Health Professions, Drexel University, Philadelphia, PA 19104, USA

^*

Author to whom correspondence should be addressed.

Int. J. Mol. Sci. 2021, 22(9), 4366; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22094366

Submission received: 24 March 2021 / Accepted: 26 March 2021 / Published: 22 April 2021

(This article belongs to the Section Molecular Endocrinology and Metabolism)

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Versions Notes

The authors wish to make the following corrections to this paper [1]: On page 6, the curve in Figure 5a was switched with Figure 7c on Page 7. Thus, Figure 5 should be replaced with the following figure (Figure 1), and Figure 7 with the following figure (Figure 2).

The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original article has been updated.

Conflicts of Interest

The authors declare no conflict of interest.

Reference

Paszkiewicz, R.L.; Bergman, R.N.; Santos, R.S.; Frank, A.P.; Woolcott, O.O.; Iyer, M.S.; Stefanovski, D.; Clegg, D.J.; Kabir, M. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting that Central Effects Can Be Avoided. Int. J. Mol. Sci. 2020, 21, 6639. [Google Scholar] [CrossRef] [PubMed]

Figure 1. Peripheral cannabinoid receptor 1 (CB1R) antagonist increased oxygen consumption rate (OCR). 3T3-L1 adipocytes were treated with AM6545, rimonabant (RIM), and isoproterenol (ISO) at 4 and 48 h. OCR was measured in basal conditions or in response to sequential treatment with 2 oligomycin, 0.75 FFCP (respiratory chain uncoupler), and 1 µM rotenone/antimycin A (inhibitor of respiratory chain complex I and complex III) using the Seahorse XF-24 analyzer. (A) Mitochondrial respiration curves at 4 h after treatment. (B) Parameters calculated from the tracing at 4 h after treatment. (C) Mitochondrial respiration curves 48 h after treatment. (D) Parameters calculated from the OCR at 48 h after treatment. Data on graphs are presented as the mean ± standard error of mean (SEM) of 4 independent rounds of the cells; * p < 0.05 vs. control, ** p < 0.01 vs. control.

Figure 2. Peripheral cannabinoid receptor 1 (CB1R) antagonist increased oxygen consumption rate (OCR) inhibited by lipolysis blocker. 3T3-L1 adipocytes were treated with AM6545 and rimonabant (RIM) with and without Atglinstatin, and isoproterenol (ISO) at 4 and 48 h. OCR was measured in basal conditions or in response to sequential treatment with 2 µM oligomycin, 0.75 µM FFCP (respiratory chain uncoupler), and 1 µM rotenone/antimycin A (inhibitor of respiratory chain complex I and complex III) using the Seahorse XF-24 analyzer. (A) Mitochondrial respiration tracing using Seahorse at 4 h after treatment. (B) Parameters calculated from the tracing at 4 h after treatment. (C) Mitochondrial respiration tracing 48 h after treatment. (D) Parameters calculated from the tracing at 48 h after treatment. Data on graphs are presented as the mean ± standard deviation (SD) of 4 independent rounds of the cells; * p < 0.05 vs. control, ** p < 0.01 vs. control.

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Paszkiewicz, R.L.; Bergman, R.N.; Santos, R.S.; Frank, A.P.; Woolcott, O.O.; Iyer, M.S.; Stefanovski, D.; Clegg, D.J.; Kabir, M. Correction: Paszkiewicz et al. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting That Central Effects Can Be Avoided. Int. J. Mol. Sci. 2020, 21, 6639. Int. J. Mol. Sci. 2021, 22, 4366. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22094366

AMA Style

Paszkiewicz RL, Bergman RN, Santos RS, Frank AP, Woolcott OO, Iyer MS, Stefanovski D, Clegg DJ, Kabir M. Correction: Paszkiewicz et al. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting That Central Effects Can Be Avoided. Int. J. Mol. Sci. 2020, 21, 6639. International Journal of Molecular Sciences. 2021; 22(9):4366. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22094366

Chicago/Turabian Style

Paszkiewicz, Rebecca L., Richard N. Bergman, Roberta S. Santos, Aaron P. Frank, Orison O. Woolcott, Malini S. Iyer, Darko Stefanovski, Deborah J. Clegg, and Morvarid Kabir. 2021. "Correction: Paszkiewicz et al. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting That Central Effects Can Be Avoided. Int. J. Mol. Sci. 2020, 21, 6639" International Journal of Molecular Sciences 22, no. 9: 4366. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22094366

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Correction: Paszkiewicz et al. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting That Central Effects Can Be Avoided. Int. J. Mol. Sci. 2020, 21, 6639

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