Next Article in Journal
Positive Association of Cardiovascular Disease (CVD) with Chronic Exposure to Drinking Water Arsenic (As) at Concentrations below the WHO Provisional Guideline Value: A Systematic Review and Meta-analysis
Next Article in Special Issue
Is Parent Engagement with a Child Health Home-Based Record Associated with Parents Perceived Attitude towards Health Professionals and Satisfaction with the Record? A Cross-Sectional Survey of Parents in New South Wales, Australia
Previous Article in Journal
Distress Due to Urinary Problems and Psychosocial Correlates among Retired Men in Hong Kong
Previous Article in Special Issue
Iron and Iodine Status in Pregnant Women from A Developing Country and Its Relation to Pregnancy Outcomes
Article

The Preventive Effect of Lactoferrin-Containing Yogurt on Gastroenteritis in Nursery School Children—Intervention Study for 15 Weeks

1
Department of Occupational Medicine, School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
2
Department of Preventive Medicine and Public Health, School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
3
Food Ingredients and Technology Institute, R&D Division, Morinaga Milk Industry Co., Ltd, Zama, Kanagawa 252-8583, Japan
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(7), 2534; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17072534
Received: 3 March 2020 / Revised: 3 April 2020 / Accepted: 4 April 2020 / Published: 7 April 2020
(This article belongs to the Special Issue Advances in Maternal and Child Healthcare)
To evaluate the effects of bovine lactoferrin (LF)-containing yogurt on gastroenteritis in nursery school children during the winter season, we conducted a randomized prospective study. A total of 1296 children were randomized into a group in which LF was provided in yogurt (LF group, n = 661) and a non-LF consumption group (control group, n = 635). The LF group was given LF-containing yogurt (100 mg/day) on all 5 weekdays for approximately 15 weeks, and the control group consumed fruit jelly instead of the yogurt. The final totals of 578 children as the LF group and 584 as the control group were analyzed. The total number of children who were absent from school due to vomiting was significantly lower in the LF group compared to the control, accounting for ≥3 days in any week: 10/234 (4.3%) vs. 49/584 (8.4%), respectively; p = 0.04. Regarding the relationship between absences due to vomiting and the consumption of the LF-containing yogurt, the adjusted odds ratio for absence due to vomiting was 2.48 (95% CI: 1.19–5.14) in the LF children who consumed LF-containing yogurt ≤2 days/week compared to the LF children who consumed the yogurt ≥ 3 days/week. The consumption of LF-containing yogurt (100 mg/day) for ≥3 days/week might help alleviate the symptom of vomiting in nursery school children during the winter. View Full-Text
Keywords: lactoferrin; lactoferrin-containing yogurt; nursery school children; vomiting; absent days lactoferrin; lactoferrin-containing yogurt; nursery school children; vomiting; absent days
Show Figures

Figure 1

MDPI and ACS Style

Tsukahara, T.; Fujimori, A.; Misawa, Y.; Oda, H.; Yamauchi, K.; Abe, F.; Nomiyama, T. The Preventive Effect of Lactoferrin-Containing Yogurt on Gastroenteritis in Nursery School Children—Intervention Study for 15 Weeks. Int. J. Environ. Res. Public Health 2020, 17, 2534. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17072534

AMA Style

Tsukahara T, Fujimori A, Misawa Y, Oda H, Yamauchi K, Abe F, Nomiyama T. The Preventive Effect of Lactoferrin-Containing Yogurt on Gastroenteritis in Nursery School Children—Intervention Study for 15 Weeks. International Journal of Environmental Research and Public Health. 2020; 17(7):2534. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17072534

Chicago/Turabian Style

Tsukahara, Teruomi, Anri Fujimori, Yuka Misawa, Hirotsugu Oda, Koji Yamauchi, Fumiaki Abe, and Tetsuo Nomiyama. 2020. "The Preventive Effect of Lactoferrin-Containing Yogurt on Gastroenteritis in Nursery School Children—Intervention Study for 15 Weeks" International Journal of Environmental Research and Public Health 17, no. 7: 2534. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17072534

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop