Factors Associated with Metabolic Syndrome Among Middle-Aged Women in Their 50s: Based on National Health Screening Data
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Setting and Sample
2.3. Measurements
2.3.1. Metabolic Syndrome Diagnosis Criteria
2.3.2. General Characteristics
2.3.3. Health Status and Health Behavioral Characteristics
2.4. Ethical Considerations
2.5. Statistical Analysis
3. Results
3.1. Number of Metabolic Syndrome Risk Factors
3.2. Differences in Risk Factors for Metabolic Syndrome
3.3. Differences in the Various Characteristics of the Normal and Metabolic Syndrome Groups
3.4. Factors Associated with Metabolic Syndrome among Middle-Aged Women in Their 50s
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
- Grundy, S.M.; Cleeman, J.I.; Daniels, S.R.; Donato, K.A.; Eckel, R.H.; Franklin, B.A.; Gordon, D.J.; Krauss, R.M.; Savage, P.J.; Smith, S.C.; et al. Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Circulation 2005, 112, 2735–2752. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Mottillo, S.; Filion, K.B.; Genest, J.; Joseph, L.; Pilote, L.; Poirier, P.; Rinfret, S.; Schiffrin, E.L.; Eisenberg, M.J. The Metabolic Syndrome and Cardiovascular Risk: A Systematic Review and Meta-analysis. J. Am. Coll Cardiol. 2010, 56, 1113–1132. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- National Cholesterol Education Program Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults. Third report of the National Cholesterol Education Program (NCEP) expert panel on detectio0n, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report. Circulation 2002, 106, 3143–3564. [Google Scholar] [CrossRef]
- Lim, S.; Shin, H.; Song, J.H.; Kwak, S.H.; Kang, S.M.; Yoon, J.W.; Choi, S.H.; Cho, S.I.; Park, K.S.; Lee, H.K.; et al. Increasing prevalence of metabolic syndrome in Korea. The Korean National Health and Nutrition Examination Survey for 1998–2007. Am. Diabetes Assoc. 2011, 34, 1323–1328. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Tran, B.T.; Jeong, B.Y.; Oh, J.K. The prevalence trend of metabolic syndrome and its components and risk factors in Korean adults: Results from the Korean National Health and Nutrition Examination Survey 2008-2013. BMC Public Health 2017, 17, 71. [Google Scholar] [CrossRef] [Green Version]
- Korea Centers for Disease Control and Prevention. In-Depth Analyses of the Third National Health and Nutrition Examination Survey: The Health Examination Survey Part; Korea Centers for Disease Control and Prevention: Seoul, Korea, 2007.
- Lee, H.B. Impact of physical activity level and types of activities of middle-aged women on risk factors of metabolic syndrome and energy metabolism. J. Korean Growth Dev. 2014, 22, 371–380. [Google Scholar]
- Statistics Korea. 2009 Life Tables for Korea; Statistics Korea: Daejeon, Korea, 2010. [Google Scholar]
- Haidinger, T.; Zweiműller, M.; Stütz, L.; Demir, D.; Kaider, A.; Strametz-Juranek, J. Effect of Gender on Awareness of Cardiovascular Risk Factors, Preventive Action Taken, and Barriers to Cardiovascular Health in a Group of Austrian Subjects. Gender Med. 2012, 9, 94–102. [Google Scholar] [CrossRef]
- Kweon, Y.R.; Jeon, H.O. Effects of Perceived Health Status, Self-esteem and Family Function on Expectations Regarding Aging among Middle-aged Women. J. Korean Acad. Nur. 2013, 43, 176–184. [Google Scholar] [CrossRef] [Green Version]
- Yun, Y.S. Obesity in women: Effect of pregnancy and menopause. Korean J. Fam. Med. 2002, 23, 553–563. [Google Scholar]
- Braun, S.; Bitton-Worms, K.; LeRoith, D. The link between the metabolic syndrome and cancer. Int. J. Biol. Sci. 2011, 7, 1003–1015. [Google Scholar] [CrossRef]
- Bang, S.Y.; Cho, I.G. The effects of menopause on the metabolic syndrome in Korean women. J. Korea Acad. Industr. Coop. Soc. 2015, 16, 2704–2712. [Google Scholar] [CrossRef]
- Im, M.Y.; Lee, Y.R.; Han, S.J.; Cho, C.M. The Effects of Lifestyle Factors on Metabolic Syndrome among Korean Adults. J. Korean Acad. Community Health Nurs. 2012, 23, 13–21. [Google Scholar] [CrossRef]
- Seo, J.M.; Lim, N.K.; Lim, J.Y.; Park, H.Y. Gender Difference in Association with Socioeconomic Status and Incidence of Metabolic Syndrome in Korean Adults. Korean J. OBES 2016, 25, 247–254. [Google Scholar] [CrossRef] [Green Version]
- Lee, H.M.; Kam, S.; Jin, S.H. The Affecting Factors of Metabolic Syndrome in Korean Adults in Their 30s and 40s. J. Korean Health Serv. Manag. 2018, 12, 143–156. [Google Scholar] [CrossRef]
- Myong, J.P.; Kim, H.R.; Jung-Choi, K.; Baker, D.; Choi, B. Disparities of metabolic syndrome prevalence by age, gender and occupation among Korean adult workers. Ind. Health 2012, 50, 115–122. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Cho, K.I.; Kim, B.H.; Je, H.G.; Jang, J.S.; Park, Y.H. Gender-Specific associations between socioeconomic status and psychological factors and metabolic syndrome in the Korean population: Findings from the 2013 Korean National Health and Nutrition Examination Survey. BioMed. Res. 2016, 2016, 3973197. [Google Scholar] [CrossRef]
- Trivedi, T.; Liu, J.; Probst, J.C.; Martin, A.B. The metabolic syndrome: Are rural residents at increased risk? J. Rural Health 2013, 29, 188–197. [Google Scholar] [CrossRef]
- Kang, H.T.; Kim, S.Y.; Kim, J.; Kim, J.; Kim, J.; Park, H.A.; Shin, J.Y.; Cho, S.H.; Choi, Y.G.; Shim, J.Y. Clinical practice guideline of prevention and treatment for metabolic syndrome. Korean J. Fam. Pract. 2015, 5, 375–420. [Google Scholar]
- Sakuraya, A.; Watanabe, K.; Kawakami, N.; Imamura, K.; Ando, E.; Asai, Y.; Eguchi, H.; Kobayashi, Y.; Nishida, N.; Arima, H.; et al. Work-related psychosocial factors and onset of metabolic syndrome among workers: A systematic review and meta-analysis protocol. BMJ Open 2017, 7, e016716. [Google Scholar] [CrossRef]
- Kim, M.K.; Lee, W.Y.; Kang, J.H.; Kang, J.H.; Kim, B.T.; Kim, S.M.; Kim, E.M.; Suh, S.H.; Shin, H.J.; Lee, K.R.; et al. 2014 clinical practice guidelines for overweight and obesity in Korea. Endocrinol. Metab. 2014, 29, 405–409. [Google Scholar] [CrossRef] [Green Version]
- Lee, S.Y.; Park, H.S.; Kim, D.J.; Han, J.H.; Kim, S.M.; Cho, G.J.; Kim, D.Y.; Kwon, H.S.; Kim, S.R.; Lee, C.B.; et al. Appropriate waist circumference cutoff points for central obesity in Korean adults. Diabetes Res. Clin. Pract. 2007, 75, 72–80. [Google Scholar] [CrossRef] [PubMed]
- Kim, I.H.; Chun, H. Employment and married women’s health in Korea; beneficial or harmful? J. Prev. Med. Public Health 2009, 42, 323–330. [Google Scholar] [CrossRef]
- Drewnowski, A.; Specter, S.E. Poverty and obesity: The role of energy density and energy costs. Am. J. Clin. Nutr. 2004, 79, 6–16. [Google Scholar] [CrossRef] [PubMed]
- Dallongeville, J.; Cottel, D.; Ferrières, J.; Arveiler, D.; Bingham, A.; Ruidavets, J.B. Household Income Is Associated with the Risk of Metabolic syndrome in a Sex-Specific Manner. Diabetes Care 2005, 28, 409–415. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Kim, D.J. The association of socioeconomic status with diabetes, and cardiovascular disease. Korean J. Med. 2008, 74, 349–357. [Google Scholar]
- KIM, E.G.; Oh, S.W. Gender Differences in the Association of Occupation with Metabolic Syndrome in Korean Adults. J. OBES Metab. Syndr. 2012, 21, 108–114. [Google Scholar] [CrossRef]
- Zhou, H.C.; Lai, Y.X.; Shan, Z.Y.; Jia, W.P.; Yang, W.Y.; Lu, J.M.; Weng, J.P.; Ji, L.N.; Liu, J.; Tian, H.; et al. Effectiveness of different waist circumference cut-off values in predicting metabolic syndrome prevalence and risk factors in adults in China. Biomed. Environ. Sci. 2014, 27, 325–334. [Google Scholar] [CrossRef]
- Ebrahim, S.; Kinra, S.; Bowen, L.; Andersen, E.; Ben-Shlomo, Y.; Lyngdoh, T.; Ramakrishnan, L.; Ahuja, R.C.; Joshi, P.; Mohan Das, S.; et al. The effect of rural-to-urban migration on obesity and diabetes in India: A cross-sectional study. PLoS Med. 2010, 7, e1000268. [Google Scholar] [CrossRef]
- Wang, Q.; Chair, S.Y.; Wong, E.M. The effects of a lifestyle intervention program on physical outcomes, depression, and quality of life in adults with metabolic syndrome: A randomized clinical trial. Int. J. Cardiol. 2017, 230, 461–467. [Google Scholar] [CrossRef]
- Monteiro, C.A.; Moura, E.C.; Conde, W.L.; Popkin, B.M. Socioeconomic status and obesity in adult populations of developing countries: A review. Bull. World Health Organ. 2004, 82, 940–946. [Google Scholar]
- Padilla, H.; Gaziano, J.M.; Djousse, L. Alcohol consumption and risk of heart failure: A meta-analysis. Phys. Sportsmed. 2010, 38, 84–89. [Google Scholar] [CrossRef] [PubMed]
- Freiberg, M.S.; Cabral, H.J.; Heeren, T.C.; Vasan, R.S.; Curtis, E.R. Alcohol consumption and the prevalence of the metabolic syndrome in the US. Diabetes Care 2004, 27, 2954–2959. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Oh, S.W. Effects of alcohol on obesity and metabolic syndrome. Korean J. OBES 2009, 18, 1–7. [Google Scholar]
- Laaksonen, D.E.; Lakka, H.M.; Salonen, J.T.; Niskanen, L.K.; Rauramaa, R.; Lakka, T.A. Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome. Diabetes Care 2002, 25, 1612–1618. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Reutter, L.; Kushner, K.E. Health equity through action on the social determinants of health: Taking up the challenge in nursing. Nurs. Inquiry 2010, 17, 269–280. [Google Scholar] [CrossRef] [PubMed]
- Khazaeian, S.; Kariman, N.; Ebadi, A.; Nasiri, M. The impact of social capital and social support on the health of female-headed households: A systematic review. Electr. Phys. 2017, 9, 6027–6034. [Google Scholar] [CrossRef] [Green Version]
Number of Risk Factors | n (%) | |
---|---|---|
0 | 11,765 | (32.2) |
1 | 11,865 | (32.4) |
2 | 7598 | (20.8) |
3 | 3754 | (10.3) |
4 | 1358 | (3.7) |
5 | 242 | (0.7) |
Total | 36,582 | (100.0) |
Characteristics | Non-MetS (n = 31,228) | MetS (n = 5354) | t | p |
---|---|---|---|---|
WC (cm) | 75.44 ± 6.99 | 83.77 ± 8.22 | −69.84 | <0.001 |
Triglyceride (mg/dL) | 102.00 ± 56.58 | 188.30 ± 93.33 | −65.54 | <0.001 |
HDL-C (mg/dL) | 61.00 ± 20.46 | 47.84 ± 13.69 | 59.81 | <0.001 |
SBP (mmHg) | 118.00 ± 13.58 | 130.90 ± 13.77 | −63.76 | <0.001 |
DBP (mmHg) | 73.83 ± 9.31 | 80.90 ± 9.43 | −51.27 | <0.001 |
FG (mg/dL) | 93.29 ± 15.87 | 110.90 ± 31.18 | −40.37 | <0.001 |
Characteristics | Total (N = 36,582) | Non-MetS (N = 31,228) | MetS (N = 5354) | χ2 | p | |||||
---|---|---|---|---|---|---|---|---|---|---|
Demographic factor | Job | No | 13,112 | (35.8) | 10,808 | (34.6) | 2304 | (43.0) | 141.02 | <0.001 |
Yes | 23,470 | (64.2) | 20,420 | (65.4) | 3050 | (57.0) | ||||
Income | Low(0–6) | 21,741 | (59.4) | 18,343 | (58.8) | 3398 | (63.5) | 110.67 | <0.001 | |
Medium(7–9) | 9525 | (26.1) | 8099 | (25.9) | 1426 | (26.6) | ||||
High(10) | 5316 | (14.5) | 4786 | (15.3) | 530 | (9.9) | ||||
Residence | Seoul | 5870 | (16.0) | 5145 | (16.5) | 725 | (13.5) | 54.50 | <0.001 | |
City | 10,847 | (29.7) | 9361 | (30.0) | 1486 | (27.8) | ||||
Country | 19,865 | (54.3) | 16,722 | (53.5) | 3143 | (58.7) | ||||
Health status | BMI | Underweight | 843 | (2.3) | 829 | (2.6) | 14 | (0.3) | 3187.5 | <0.001 |
Normal | 25,891 | (70.8) | 23,677 | (75.8) | 2214 | (41.4) | ||||
Overweight or Obese | 9844 | (26.9) | 6719 | (21.5) | 3125 | (58.4) | ||||
Total cholesterol | Normal | 30,143 | (82.4) | 25,923 | (83.0) | 4220 | (78.8) | 55.62 | <0.001 | |
Abnormal | 6436 | (17.6) | 5302 | (17.0) | 1134 | (21.2) | ||||
LDL-cholesterol | Normal | 21,043 | (58.0) | 18,027 | (58.1) | 3016 | (57.0) | 2.19 | 0.997 | |
Abnormal | 15,261 | (42.0) | 12,989 | (41.9) | 2272 | (43.0) | ||||
Health behavior | Smoking | Non | 36,080 | (98.8) | 30,816 | (98.8) | 5264 | (98.5) | 3.71 | 0.054 |
Smoker | 455 | (1.2) | 374 | (1.2) | 81 | (1.5) | ||||
Drinking | Non | 30,205 | (82.6) | 25,658 | (82.2) | 4547 | (85.0) | 31.85 | <0.001 | |
Moderate | 5141 | (14.1) | 4521 | (14.5) | 620 | (11.6) | ||||
High risk | 1209 | (3.3) | 1025 | (3.3) | 184 | (3.4) | ||||
Exercise | Non | 18,824 | (51.5) | 15,853 | (50.8) | 2971 | (55.5) | 49.14 | <0.001 | |
Walking | 6577 | (18.0) | 5629 | (18.0) | 948 | (17.7) | ||||
More than moderate | 11,181 | (30.5) | 9746 | (31.2) | 1435 | (26.8) | ||||
Past history | DM | No | 35,039 | (95.8) | 30,403 | (97.4) | 4636 | (86.6) | 1311.89 | <0.001 |
Yes | 1543 | (4.2) | 825 | (2.6) | 718 | (13.4) | ||||
Hypertension | No | 30,261 | (82.7) | 26,736 | (85.6) | 3525 | (65.8) | 1250.65 | <0.001 | |
Yes | 6321 | (17.3) | 4492 | (14.4) | 1829 | (34.2) | ||||
Stroke | No | 36,436 | (99.6) | 31,109 | (99.6) | 5327 | (99.5) | 1.75 | 0.186 | |
Yes | 146 | (0.4) | 119 | (0.4) | 27 | (0.5) | ||||
Dyslipidemia | No | 34,854 | (95.3) | 29,877 | (95.7) | 4977 | (93.0) | 74.87 | <0.001 | |
Yes | 1728 | (4.7) | 1351 | (4.3) | 377 | (7.0) | ||||
Family history | DM | No | 32,606 | (89.1) | 27,986 | (89.6) | 4620 | (86.3) | 52.24 | <0.001 |
Yes | 3976 | (10.9) | 3242 | (10.4) | 734 | (13.7) | ||||
Hypertension | No | 30,718 | (84.0) | 26,396 | (84.5) | 4322 | (80.7) | 49.08 | <0.001 | |
Yes | 5864 | (16.0) | 4832 | (15.5) | 41,032 | (19.3) | ||||
Stroke | No | 33,282 | (91.0) | 28,413 | (91.0) | 4869 | (90.9) | 0.01 | 0.917 | |
Yes | 3300 | (9.0) | 2815 | (9.0) | 485 | (9.1) |
Characteristics | OR (95% CI) | p | |||
---|---|---|---|---|---|
Intercept | <0.001 | ||||
Demographic factor | Job (ref: No) | Yes | 1.28 | (1.20–1.36) | <0.001 |
Income (ref: Low) | Medium | 0.95 | (0.89–1.03) | 0.213 | |
High | 0.73 | (0.66–0.81) | <0.001 | ||
Residence (ref: Seoul) | City | 1.07 | (0.96–1.18) | 0.174 | |
Country | 1.15 | (1.04–1.26) | 0.005 | ||
Health status | BMI (ref: Normal) | Underweight | 0.19 (0.11–0.33) | <0.001 | |
Overweight or Obese | 4.26 | (3.99–4.53) | <0.001 | ||
Total cholesterol (ref: Normal) | Abnormal | 1.33 | (1.23–1.44) | <0.001 | |
Health behavior | Drinking (ref: No) | Moderate | 0.76 | (0.69–0.84) | <0.001 |
High risk | 0.86 | (0.72–1.02) | 0.094 | ||
Exercise (ref: No) | Walking | 0.90 | (0.82–0.98) | 0.013 | |
More than moderate | 0.83 | (0.77–0.90) | <0.001 | ||
Past history | Stroke (ref: No) | Yes | 0.92 | (0.58–1.46) | 0.723 |
DM (ref: No) | Yes | 4.14 | (3.67–4.66) | <0.001 | |
Dyslipidemia (ref: No) | Yes | 1.08 | (0.95–1.23) | 0.253 | |
Hypertension (ref: No) | Yes | 2.14 | (1.99–2.31) | <0.001 | |
Family history | Stroke (ref: No) | Yes | 0.96 | (0.86–1.08) | 0.523 |
DM (ref: No) | Yes | 1.15 | (1.04–1.27) | 0.006 | |
Hypertension (ref: No) | Yes | 1.02 | (0.93–1.11) | 0.694 |
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Share and Cite
Kim, H.; Cho, Y. Factors Associated with Metabolic Syndrome Among Middle-Aged Women in Their 50s: Based on National Health Screening Data. Int. J. Environ. Res. Public Health 2020, 17, 3008. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17093008
Kim H, Cho Y. Factors Associated with Metabolic Syndrome Among Middle-Aged Women in Their 50s: Based on National Health Screening Data. International Journal of Environmental Research and Public Health. 2020; 17(9):3008. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17093008
Chicago/Turabian StyleKim, HyungSeon, and YeonHee Cho. 2020. "Factors Associated with Metabolic Syndrome Among Middle-Aged Women in Their 50s: Based on National Health Screening Data" International Journal of Environmental Research and Public Health 17, no. 9: 3008. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17093008