Recent studies have shown a correlation between
Helicobacter pylori (
H. Pylori) infection and the neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR). The aim of this study was to investigate the relationship between
H. Pylori infection and hematimetric indices in patients with
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Recent studies have shown a correlation between
Helicobacter pylori (
H. Pylori) infection and the neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR). The aim of this study was to investigate the relationship between
H. Pylori infection and hematimetric indices in patients with dyspepsia symptoms. Overall, 448 patients who underwent gastroscopy were analyzed retrospectively. Histopathological evaluation of biopsies according to
H. pylori presence was classified as
H. Pylori positive and negative groups, which are analyzed in relation with hematimetric indices. NLR and PLR measurements did not show a statistically significant difference between
H. pylori negative and positive groups (
p > 0.05). NLR revealed a negative correlation between hemoglobin (HGB), iron, and ferritin measurements in the correlation analysis of the
H. Pylori positive group (r = −0.133,
p = 0.031; r = −0.270,
p = 0.002; r = −0.162,
p = 0.032). Again, with PLR, there was a negative correlation between HGB, mean corpuscular volume (MCV), iron, and ferritin measurements (r = −0.310,
p = 0.001, r = −0.187,
p = 0.002, r = −0.335,
p = 0.001; r = −0.290;
p = 0.001). The results of our study do not reveal an association between
H. pylori presence and inflammatory response, which is evaluated by NLR and PLR measurements in patients with dyspepsia. However, low serum iron and ferritin values of
H. pylori-positive patients suggest the effect of
H. pylori on iron metabolism.
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