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Review

Curcumin against Prostate Cancer: Current Evidence

1
Department of Health Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada
2
Centre for Bone and Muscle Health, Brock University, St. Catharines, ON L2S 3A1, Canada
*
Author to whom correspondence should be addressed.
Received: 7 October 2020 / Revised: 30 October 2020 / Accepted: 4 November 2020 / Published: 10 November 2020
(This article belongs to the Special Issue Biomolecules and Cancer Prevention)
Cancer is a condition characterized by remarkably enhanced rates of cell proliferation paired with evasion of cell death. These deregulated cellular processes take place following genetic mutations leading to the activation of oncogenes, the loss of tumor suppressor genes, and the disruption of key signaling pathways that control and promote homeostasis. Plant extracts and plant-derived compounds have historically been utilized as medicinal remedies in different cultures due to their anti-inflammatory, antioxidant, and antimicrobial properties. Many chemotherapeutic agents used in the treatment of cancer are derived from plants, and the scientific interest in discovering plant-derived chemicals with anticancer potential continues today. Curcumin, a turmeric-derived polyphenol, has been reported to possess antiproliferative and proapoptotic properties. In the present review, we summarize all the in vitro and in vivo studies examining the effects of curcumin in prostate cancer. View Full-Text
Keywords: prostate cancer; proliferation; apoptosis; survival; androgen-sensitive; androgen-insensitive; polyphenol; curcumin; in vitro; in vivo prostate cancer; proliferation; apoptosis; survival; androgen-sensitive; androgen-insensitive; polyphenol; curcumin; in vitro; in vivo
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MDPI and ACS Style

Termini, D.; Den Hartogh, D.J.; Jaglanian, A.; Tsiani, E. Curcumin against Prostate Cancer: Current Evidence. Biomolecules 2020, 10, 1536. https://0-doi-org.brum.beds.ac.uk/10.3390/biom10111536

AMA Style

Termini D, Den Hartogh DJ, Jaglanian A, Tsiani E. Curcumin against Prostate Cancer: Current Evidence. Biomolecules. 2020; 10(11):1536. https://0-doi-org.brum.beds.ac.uk/10.3390/biom10111536

Chicago/Turabian Style

Termini, Deborah, Danja J. Den Hartogh, Alina Jaglanian, and Evangelia Tsiani. 2020. "Curcumin against Prostate Cancer: Current Evidence" Biomolecules 10, no. 11: 1536. https://0-doi-org.brum.beds.ac.uk/10.3390/biom10111536

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