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Review
Peer-Review Record

The Biological Efficacy of Natural Products against Acute and Chronic Inflammatory Diseases in the Oral Region

by Toshiaki Ara 1, Sachie Nakatani 2, Kenji Kobata 2, Norio Sogawa 1 and Chiharu Sogawa 3,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Submission received: 26 October 2018 / Revised: 8 November 2018 / Accepted: 8 November 2018 / Published: 13 November 2018

Round  1

Reviewer 1 Report

Manuscript medicines-387005 presents a review of the effectiveness of Japanese traditional herbal medicines (kampo) against acute and chronic oral inflammations.  The review is well organized and informative.  Publication in Medicines is recommended after minor, mostly editorial, revision.

Line 68:  Stephania cephalantha Hayata [correct the spelling]

Line 118:  Periodontitis [capitalize]

Tables 2-7:  I think a column including the Linnean binomial (along with the botanical authority) should also be included.

Line 376:  japonica [correct the spelling]

Line 377:  Ranunculaceae [not italicized]

Line 424:  Include the botanical autority with these scientific names:  Diospyros kaki Thunb. and Physalis alkekengi L.

Line 451:  Salacia reticulata Wight


Author Response

see the attachment

Author Response File: Author Response.pdf

Reviewer 2 Report

This review is very interesting since it describes the anti-inflammatory effects of herbal medicines on oral diseases and in particular on periodontal disease treatment. This paper meet a high standard of scientific quality and credibility.  It is readable and appropriately presented, and  contains appropriate referencing and any recognizable plagiarism. This paper Is compliant with the aims and scope of the journal and  meet ethical requirements.


Author Response

Thank you very much for your comments.

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